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B5453

Sigma-Aldrich

2-Benzimidazolylurea

98%

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About This Item

Empirical Formula (Hill Notation):
C8H8N4O
CAS Number:
Molecular Weight:
176.18
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

form

powder

mp

>300 °C (lit.)

SMILES string

NC(=O)Nc1nc2ccccc2[nH]1

InChI

1S/C8H8N4O/c9-7(13)12-8-10-5-3-1-2-4-6(5)11-8/h1-4H,(H4,9,10,11,12,13)

InChI key

LNYZEFQMIURYEI-UHFFFAOYSA-N

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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S Trivulzio
Pharmacological research communications, 20(12), 1035-1046 (1988-12-01)
2-Benzimidazolylurea (BIU) decreases gastric acid secretion. The antisecretive activity appears to be associated with antihistaminic and antimuscarinic effects. The antihistaminic activity of BIU appears from its inhibitory effects on betazole stimulated gastric acid secretion and from its inhibitory activity on
R S Gupta
Biochemical and biophysical research communications, 143(1), 225-232 (1987-02-27)
The cross resistance patterns of a set of nocodazole-resistant (NocR) and podophyllotoxin-resistant (PodR) mutants of Chinese hamster ovary cells, which exhibit highly specific cross resistance towards compounds that show nocodazole-like antimitotic activity, towards a large number of benzimidazole derivatives have
Liang Hong et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(27), 9971-9976 (2014-06-10)
The voltage-gated proton channel Hv1 plays important roles in proton extrusion, pH homeostasis, and production of reactive oxygen species in a variety of cell types. Excessive Hv1 activity increases proliferation and invasiveness in cancer cells and worsens brain damage in

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