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ALD00600

Sigma-Aldrich

Zhu-Yu Auxiliary

98%

Synonym(s):

1-Carboxy-1-methylethoxyammonium chloride, 2,2-Dimethyl aminooxyacetic, 2-(Aminooxy)-2-methylpropanoic acid hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C4H10ClNO3
CAS Number:
Molecular Weight:
155.58
MDL number:
UNSPSC Code:
12352101

Assay

98%

form

powder or crystals

reaction suitability

reaction type: C-C Bond Formation
reagent type: catalyst
reagent type: ligand
reaction type: C-H Activation

availability

available only in USA

mp

150-165 °C

InChI

1S/C4H9NO3.ClH/c1-4(2,8-5)3(6)7;/h5H2,1-2H3,(H,6,7);1H

InChI key

ZJPZGAAOCIFBDI-UHFFFAOYSA-N

Application

The Zhu-Yu Auxiliary was reported by Jin-Quan Yu′s lab to be an effective auxiliary for the Pd(II)-catalyzed ß-C(sp3)-H(hetero)arylation of ketones.

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Pictograms

Flame

Signal Word

Danger

Hazard Statements

Hazard Classifications

Self-react. C

Storage Class Code

5.2 - Organic peroxides and self-reacting hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Related Content

The Yu program centers around the discovery of catalytic carbon–carbon and carbon–heteroatom bond forming reactions based on C–H activation. Target transformations are selected to enable 1) the use of simple and abundant starting materials such as aliphatic acids, amines and alcohols, and 2) disconnections that drastically shorten the synthesis of a drug molecule or a major class of biologically active compounds.

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