900662
Poly(D,L-lactide-co-glycolide)(85/15)-b-poly(ethylene glycol)-carboxylic acid
5k-13k
Synonym(s):
PLGA-PEG, PLGA-PEG Carboxylic acid diblock copolymer, PLGA-PEG-COOH, PLGA-b-PEG
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About This Item
Linear Formula:
HO(CH(CH3)COO)x(CH2COO)y(CH2CH2O)nH
UNSPSC Code:
12352106
NACRES:
NA.23
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Application
Biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic Poly(lactide-co-glycolide) (PLGA) block, functionalized with a terminal carboxylic acid. These materials have been used in control release and nanoparticle formulation for drug delivery applications. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Additionally, the ratio of lactide to glycolide can be tuned to control rate of degradation. Carboxylic acid termination allows for facile further chemical modification of these materials.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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