567655

5-Methoxy-3-indolylacetonitrile

95%

• Synonym(s): 3-(Cyanomethyl)-5-methoxyindole
• Empirical Formula (Hill Notation): C₁₁H₁₀N₂O
• CAS Number: 2436-17-1
• Molecular Weight: 186.21
• MDL number: MFCD02094163
• UNSPSC Code: 12352100
• PubChem Substance ID: 24880382
• NACRES: NA.22

Properties

• Assay: 95%
• mp: 65-69 °C (lit.)
• SMILES string: COc1ccc2[nH]cc(CC#N)c2c1
• InChI: 1S/C11H10N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4H2,1H3
• InChI key: ZBQCXEREMRGOCO-UHFFFAOYSA-N

Description

Application

Reactant for preparation of (-)- and (+)-debromoflustramine B and its analogues as selective butyrylcholinesterase inhibitors
Reactant for preparation of carboline analogs as potent MAPKAP-K2 inhibitors
Reactant for preparation of indole-N-acetic acid derivatives as aldose reductase inhibitors for diabetic complications treatment
Reactant for preparation of debromoflustramine B and labeled Me(3a)-13C-physostigmine
Reactant for preparation of physostigmine and physovenine
Reactant for preparation of phenethyl substituted indole derivatives as melatoninergic agonists and antagonists

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves