549967

2,4,6-Tri-tert-butylpyrimidine

97%

• Synonym(s): 2,4,6-Tris(1,1-dimethylethyl)pyrimidine
• Empirical Formula (Hill Notation): C₁₆H₂₈N₂
• CAS Number: 67490-21-5
• Molecular Weight: 248.41
• MDL number: MFCD03094045
• UNSPSC Code: 12352100
• PubChem Substance ID: 24874736
• NACRES: NA.22

Properties

• Assay: 97%
• mp: 77-80 °C (lit.)
• SMILES string: CC(C)(C)c1cc(nc(n1)C(C)(C)C)C(C)(C)C
• InChI: 1S/C16H28N2/c1-14(2,3)11-10-12(15(4,5)6)18-13(17-11)16(7,8)9/h10H,1-9H3
• InChI key: VYWSYEDVFVGRGG-UHFFFAOYSA-N

Description

General description

2,4,6-Tri-tert-butylpyrimidine (TTBP) is a non-hygroscopic sterically hindered base. It can be prepared by the reaction between tert-butyl methyl ketone and tert-butyronitrile.3 TTBP is a suitable alternative to 2,6-di-tert-butylated pyridines in glycosylation reactions.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves