415324

N-Isopropylacrylamide

97%

• Synonym(s): NIPAM
• Linear Formula: H₂C=CHCONHCH(CH₃)₂
• CAS Number: 2210-25-5
• Molecular Weight: 113.16
• EC Number: 218-638-5
• MDL number: MFCD00041913
• UNSPSC Code: 12162002
• PubChem Substance ID: 24865991
• NACRES: NA.23

Properties

• Assay: 97%
• bp: 89-92 °C/2 mmHg (lit.)
• mp: 60-63 °C (lit.)
• SMILES string: CC(C)NC(=O)C=C
• InChI: 1S/C6H11NO/c1-4-6(8)7-5(2)3/h4-5H,1H2,2-3H3,(H,7,8)
• InChI key: QNILTEGFHQSKFF-UHFFFAOYSA-N

Description

General description

N-Isopropylacrylamide (NIPAM) is a biocompatible monomeric unit that can be used in the formation of stimuli responsive polymers due to its temperature sensitive properties, which include temperature-based volumetric and phase changes. These properties change when the temperature of the solution reaches a lower critical solution temperature (LCST).

Application

Monomer used in the preparation of thermally sensitive, water-swellable hydrogels.

NIPAM can be used to prepare poly(NIPAM) based thermosetting polymers, which can be used for a variety of applications such as tissue engineering, cell culture, biomedical coating, drug delivery, and muscle regeneration.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H318
• Precautionary Statements: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves