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Sigma-Aldrich

Semicarbazide

6 wt. % (on silica gel)

Synonym(s):

Aminourea, Hydrazinecarboxamide, Isosemicarbazide

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About This Item

Linear Formula:
H2NCONHNH2
CAS Number:
57-56-7
Molecular Weight:
75.07
MDL number:
MFCD00042824
UNSPSC Code:
12352125
PubChem Substance ID:
24862206
NACRES:
NA.22

form

powder

composition

, 6 wt. % (on silica gel)

SMILES string

NNC(N)=O

InChI

1S/CH5N3O/c2-1(5)4-3/h3H2,(H3,2,4,5)

InChI key

DUIOPKIIICUYRZ-UHFFFAOYSA-N

Related Categories

Application

  • Antibacterial activity: Semicarbazide derivatives, specifically thiosemicarbazide, exhibit significant antibacterial properties influenced by substituent position. This underscores its application in pharmaceutical synthesis and microbial resistance studies (Janowska et al., 2024).
  • Solar cell performance: The application of semicarbazide hydrochloride in suppressing deep-level traps significantly improves the efficiency of tin-based perovskite solar cells, highlighting its potential in energy materials research (Jia et al., 2023).

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M M Palcic et al.
Progress in brain research, 106, 41-47 (1995-01-01)
The relationship between the soluble copper topaquinone amine oxidases, the membrane bound semicarbazide-sensitive amine oxidases and lysyl oxidase remains unclear. The stereochemical course of substrate oxidation has been determined for each enzyme type and these studies suggest that SSAO and
Sathya Narayanan Patmanathan et al.
Scientific reports, 6, 25650-25650 (2016-05-11)
Oral squamous cell carcinoma (OSCC) is a lethal disease with a 5-year mortality rate of around 50%. Molecular targeted therapies are not in routine use and novel therapeutic targets are required. Our previous microarray data indicated sphingosine 1-phosphate (S1P) metabolism
Palak J Trivedi et al.
Gut, 67(6), 1135-1145 (2017-04-22)
Primary sclerosing cholangitis (PSC) is the classical hepatobiliary manifestation of IBD. This clinical association is linked pathologically to the recruitment of mucosal T cells to the liver, via vascular adhesion protein (VAP)-1-dependent enzyme activity. Our aim was to examine the
Christian Carpéné et al.
Journal of physiology and biochemistry, 73(3), 475-486 (2016-10-22)
Semicarbazide-sensitive amine oxidase (SSAO), identical to primary amine oxidase or vascular adhesion protein-1, is a membrane enzyme that generates hydrogen peroxide. SSAO is highly expressed at the adipocyte surface, and its plasma levels increase with type 2 diabetes. Since visceral
Kangkang Wang et al.
ACS omega, 5(30), 18887-18893 (2020-08-11)
Nitrofuran (NF) is a class of broad-spectrum antibiotics that are used illegally in animal feeding. NF and its metabolites have proven to pose potential risk to human health. To address the current analytical needs to quantify low levels of NF
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