246255

5,6-Dimethoxyindole

99%

• Empirical Formula (Hill Notation): C₁₀H₁₁NO₂
• CAS Number: 14430-23-0
• Molecular Weight: 177.20
• Beilstein: 5683
• EC Number: 238-402-5
• MDL number: MFCD00005675
• UNSPSC Code: 12352100
• PubChem Substance ID: 24854798
• NACRES: NA.22

Properties

• Assay: 99%
• form: solid
• mp: 154-157 °C (lit.)
• SMILES string: COc1cc2cc[nH]c2cc1OC
• InChI: 1S/C10H11NO2/c1-12-9-5-7-3-4-11-8(7)6-10(9)13-2/h3-6,11H,1-2H3
• InChI key: QODBZRNBPUPLEZ-UHFFFAOYSA-N

Description

Application

5,6-Dimethoxyindole was used in the synthesis of N-benzyl-N-cyclopropyl-5,6-dimethoxyindole-3-glyoxalamide.

• Reactant in synthesis of indolylhydroxyoxindoles via enantioselective Friedel-Crafts reaction
• Reactant in synthesis of benzyl trimethoxyindoles
• Reactant for synthesis of benzoylpiperazinyl-indolyl ethane dione derivatives as HIV-1 inhibitors
• Reactant for synthesis of 1-aroylindole 3-aroylindoles combretastatin A-4 analogs as antitumor agents and tubulin polymerization inhibitors
• Reactant for preparation of tryptophanol derivatives via the Grignard reaction

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves