Poly(propylene glycol) (PPG) is a biocompatible polymer widely used as a precursor to fabricate biomedical materials. It is soluble in water at low temperatures and becomes insoluble at high temperatures.
Application
Poly(propylene glycol) can be used:
As a precursor to synthesize multiblock thermo-responsive smart polymers for various biomedical applications. The presence of PPG is the main reason for the thermosensitivity of these polymers. For example, it can be used to synthesize poly(ester urethane)s.
For the surface modification of sisal fiber to enhance nucleating ability.
Journal of biomedical materials research. Part B, Applied biomaterials, 105(8), 2232-2243 (2016-07-23)
Despite its common usage in vertebral augmentation procedures (VAPs), shortcomings of commercial polymethylmethacrylate (PMMA) still remain. Accordingly, injectable and biodegradable composite cements, which are composed of poly(propylene fumarate)/α-tricalcium/hydroxyapatite (PPF/α-TCP/HAP) and PPF/tetracalcium phosphate/dicalcium phosphate (PPF/TtCP/DCP), were developed. A porcine model was
The controlled atom transfer radical polymerization of an ionic liquid, 1-(11-acryloylundecyl)-3-methyl imidazolium bromide (ILBr), from both ends of a telechelic poly(propylene oxide) (PPO) macroinitiator, end-functionalized with bromoisobutyryloyl is reported. The resulting highly water-soluble triblock, poly(ILBr-b-PO-b-ILBr) is multistimuli responsive. This new
Current treatments for cerebral aneurysms are far from ideal. Platinum coils are prone to compaction, and currently used liquid embolics are delivered with angiotoxic agents. This work presents initial in vivo studies of a novel liquid-to-solid gelling polymer system (PPODA-QT)
Physical chemistry chemical physics : PCCP, 13(27), 12571-12577 (2011-06-15)
The study highlighted the main forces driving the formation of hydroxypropyl-cyclodextrins (HP-CDs) + poly(propylene) glycol 725 g mol(-1) inclusion complexes. The temperature parameter was chosen as the variable to modulate the hydrophobicity of the polymer, and consequently ITC experiments as
Journal of biomedical nanotechnology, 8(2), 280-289 (2012-04-21)
In the last few decades, nanotechnology has led to an advance in the development of topical drug delivery. Nanostructured drug delivery systems enable the compartmentalization of drugs in restricted environments, modifying the release profile and maintaining the required drug concentration
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