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49055

Supelco

Parathion-methyl

PESTANAL®, analytical standard

Synonym(s):

O,O-Dimethyl O-(4-nitrophenyl) phosphorothioate, Methyl parathion

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About This Item

Empirical Formula (Hill Notation):
C8H10NO5PS
CAS Number:
Molecular Weight:
263.21
Beilstein:
8905814
EC Number:
MDL number:
UNSPSC Code:
12000000
PubChem Substance ID:

grade

analytical standard

product line

PESTANAL®

CofA

current certificate can be downloaded

packaging

ampule of 500 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

storage temp.

room temp

SMILES string

COP(=S)(OC)Oc1ccc(cc1)[N+]([O-])=O

InChI

1S/C8H10NO5PS/c1-12-15(16,13-2)14-8-5-3-7(4-6-8)9(10)11/h3-6H,1-2H3

InChI key

RLBIQVVOMOPOHC-UHFFFAOYSA-N

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General description

Parathion-methyl is an organophosphate insecticide, which is extensively used for agricultural purposes. Its mode of action involves the inactivation of the enzyme acetylcholinesterase (AChE) in insects and also mammals. It undergoes degradation by soil microorganisms to yield p-nitrophenol as the product.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Flam. Liq. 3 - STOT RE 2

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

114.8 °F - open cup

Flash Point(C)

46 °C - open cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Absorption, distribution, metabolism and excretion of daily oral doses of [14 C] methyl parathion in hens
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Toxicology Letters, 125(1), 1-10 (2001)
Isolation, characterization and identification of methyl parathion degrading bacteria from industrial waste
Vadukia, et al.
Journal of Cell and Tissue Research, 14(3), 4633-4633 (2014)
Effect of paraoxon-methyl and parathion-methyl on DNA in human lymphocytes and protective action of vitamin C
Blasiak J and Kowalik J
Pest Management Science, 55(12), 1182-1186 (1999)
Patrick B Dennis et al.
Biomacromolecules, 13(7), 2037-2045 (2012-06-02)
Organophosphates are some of the most acutely toxic compounds synthesized on an industrial scale, and organophosphorus hydrolase (OPH) has the ability to hydrolyze and inactivate a number of these chemicals. However, OPH activity is vulnerable to harsh environmental conditions that
Yanbo Zeng et al.
Journal of hazardous materials, 217-218, 315-322 (2012-04-13)
A sensitive electrochemical differential pulse voltammetry method was developed for detecting methyl parathion based on multiwalled carbon nanotubes-poly(acrylamide) (MWCNTs-PAAM) nanocomposite film modified glassy carbon electrode. The novel MWCNTs-PAAM nanocomposite, containing high content of amide groups, was synthesized by PAAM polymerizing

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