T3309
Transferrin human
≥98%
Synonym(s):
Siderophilin, partially saturated
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Recommended Products
biological source
human
Quality Level
Assay
≥98%
form
powder
Iron content
300-600 ppm
technique(s)
cell culture | stem cell: suitable
impurities
≤1.0 EU/mg endotoxin
UniProt accession no.
storage temp.
2-8°C
Gene Information
human ... TF(7018)
Looking for similar products? Visit Product Comparison Guide
General description
Transferrin is an 80 kDa serum glycoprotein, which has an half-life of 8 to 10 days. The gene is located on human chromosome 3q22.1. Transferrin is expressed in hepatocytes.
Application
Transferrin has been used:
- in isolation of epidermal stem cells and cell expansion
- to study the effect of compound treatment on transferrin uptake
- for transferrin uptake and confocal imaging
Biochem/physiol Actions
Transferrin facilitates the transfer of iron to erythron and peripheral tissues. Mutations in this gene is associated with atransferrinemia. Transferrin is required for fetal development. It is non immunogenic and transferrin-conjugated drugs inhibits cardiotoxicity and drug resistance.
Transferrin was shown to promote the proliferation of human lymphocytes. This effect is directly proportional to the level of iron present.
Analysis Note
Purity by agarose electrophoresis.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Severe hypochromic microcytic anemia in a patient with congenital atransferrinemia
Shamsian BS, et al.
Pediatric Hematology and Oncology, 26(5), 356-362 (2009)
TFRC (transferrin receptor (p90, CD71))
Dorak MT
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2009)
Nutritional issues in the patient with diabetes and foot ulcers
LITCHFORD MD
Levin and O'Neal's The Diabetic Foot, 199-217 (2008)
A Djeha et al.
British journal of haematology, 80(2), 235-241 (1992-02-01)
The effect of different forms of iron and iron-binding proteins on the proliferative response of human lymphocytes to phytohaemagglutinin (PHA) has been studied. Transferrin enhanced proliferation, the effect being proportional to the degree of iron saturation up to 100%, but
Bioengineering strategies for designing targeted cancer therapies
Alexander-Bryant AA, et al.
Advances in Cancer Research, 118(11), 1-59 (2013)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service