P3029

Phencyclidine hydrochloride

• Synonym(s): 1-(1-Phenylcyclohexyl)piperidine hydrochloride, PCP hydrochloride
• Empirical Formula (Hill Notation): C₁₇H₂₅N · HCl
• CAS Number: 956-90-1
• Molecular Weight: 279.85
• MDL number: MFCD00058208
• UNSPSC Code: 12352200
• PubChem Substance ID: 329820160
• NACRES: NA.77

Properties

• form: powder
• Quality Level: 300
• drug control: USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)
• solubility: H₂O: 11.2 mg/mL; 0.1 M HCl: 18.4 mg/mL; methanol: 30 mg/mL
• SMILES string: Cl.C1CCN(CC1)C2(CCCCC2)c3ccccc3
• InChI: 1S/C17H25N.ClH/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18;/h1,4-5,10-11H,2-3,6-9,12-15H2;1H
• InChI key: BUAJNGPDPGKBGV-UHFFFAOYSA-N

Description

Biochem/physiol Actions

σ opioid receptor agonist and psychostimulant; inhibits NMDA glutamate receptor activation by binding to an allosteric site within the ion channel.

Features and Benefits

This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Nicotinic) and Glutamate Receptors (Ion Channel Family) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301,H336
• Precautionary Statements: P301 + P310 + P330
• Hazard Classifications: Acute Tox. 3 Oral - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves