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Key Documents

C4431

Sigma-Aldrich

Citrate-phosphate-dextrose solution with adenine

Synonym(s):

CPD-A

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About This Item

UNSPSC Code:
12161700
NACRES:
NA.25

sterility

sterile-filtered

Quality Level

form

liquid

pH

5.4-6.7

storage temp.

2-8°C

General description

Citrate-phosphate-dextrose solution with adenine (CPDA) is an anticoagulant and preservative for storage of blood. It can prolong red blood cell storage life up to 35 days. It maintains platelet viability. Usage of CPDA improves post-transfusion visibility and improves glucose and ATP levels in blood.

Application

Citrate-phosphate-dextrose solution with adenine has been used as an anticoagulant during blood collection from cardiac puncture, transgenic hen egg lysozyme-ovalbumin-Duffy (HOD) mice and humans.

Biochem/physiol Actions

Useful anticoagulant for whole blood
Recommended anticoagulant: whole blood ratio is 1:9

related product

Product No.
Description
Pricing

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Measuring cell surface area and deformability of individual human red blood cells over blood storage using quantitative phase imaging
Park H, et al.
Scientific reports, 6(6), 34257-34257 (2016)
HyunJoo Park et al.
Scientific reports, 6, 34257-34257 (2016-10-05)
The functionality and viability of stored human red blood cells (RBCs) is an important clinical issue in transfusions. To systematically investigate changes in stored whole blood, the hematological properties of individual RBCs were quantified in blood samples stored for various
James C Keith et al.
Arthritis research & therapy, 7(4), R769-R776 (2005-07-01)
The human leukocyte antigen B27 (HLA-B27) transgenic rat is a model of human inflammatory bowel disease, rheumatoid arthritis and psoriasis. Studies of chronic inflammation in other rat models have demonstrated activation of the kallikrein-kinin system as well as modulation by
Krishnan MohanKumar et al.
Nature communications, 10(1), 3494-3494 (2019-08-04)
Necrotizing enterocolitis (NEC) is an idiopathic, inflammatory bowel necrosis of premature infants. Clinical studies have linked NEC with antecedent red blood cell (RBC) transfusions, but the underlying mechanisms are unclear. Here we report a neonatal murine model to investigate this
Taesik Go et al.
Scientific reports, 10(1), 8977-8977 (2020-06-04)
Digital holographic microscopy enables the recording of sample holograms which contain 3D volumetric information. However, additional optical elements, such as partially or fully coherent light source and a pinhole, are required to induce diffraction and interference. Here, we present a

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