The stability of this compound in solution has not been investigated. In general, solutions prepared fresh are recommended. However, various sources report that this material is stable when stored in Dimethylformamide at -20°C. The stability in anhydrous DMSO is expected to similar. No time frame is provided. This information has not been validated. Note that this product is packaged under nitrogen. Stock solutions should be stored likewise.
37919
Anhydrotetracycline hydrochloride
VETRANAL®, analytical standard
Synonym(s):
(4S,4aS,12aS)-4-(Dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide monohydrochloride
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About This Item
Empirical Formula (Hill Notation):
C22H22N2O7 · HCl
CAS Number:
Molecular Weight:
462.88
Beilstein:
4228856
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Pricing and availability is not currently available.
Recommended Products
grade
analytical standard
Quality Level
Agency
EPA 1694
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
storage condition
under inert gas
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
clinical testing
format
neat
SMILES string
Cl[H].[H][C@@]12Cc3c(C)c4cccc(O)c4c(O)c3C(=O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C
InChI
1S/C22H22N2O7.ClH/c1-8-9-5-4-6-12(25)13(9)17(26)14-10(8)7-11-16(24(2)3)18(27)15(21(23)30)20(29)22(11,31)19(14)28;/h4-6,11,16,25-27,31H,7H2,1-3H3,(H2,23,30);1H/t11-,16-,22-;/m0./s1
InChI key
XBSQEFHDCDFNJU-WPJNXPDPSA-N
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General description
Anhydrotetracycline (ATC) is a degradation product of tetracycline hydrochloride, a widely used antibiotic in animal breeding.[1]
Application
The analytical standard can be used as follows:
- Terahertz (THz) spectroscopy-based temperature-dependent quantitative and qualitative analysis of the antibiotic, tetracycline hydrochloride, and its three major metabolites
- Simultaneous analysis of tetracycline hydrochloride and its degradation products in a pharmaceutical formulation by Resonance Raman Spectroscopy to study stress-induced stability of the drug
- Development and validation of a liquid chromatography-tandem mass spectroscopy (LC-MS/MS) method to determine 21 antibiotic residues used as veterinary medicinal products in honey samples
- Estimation of eight tetracycline antibiotics in various environmental water samples by dispersive liquid-liquid microextraction (DLLME) followed by an ultra-high pressure liquid chromatography (UHPLC)-tunable ultraviolet detection (TUV)
Other Notes
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Repr. 1B
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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For how long can I store anhydrotetracycline hydrochloride dissolved in DMSO at -20°C?
1 answer-
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What is the correct temperature for storing ATC in the form of powder?
1 answer-
This product is stored at room temperature.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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How can I dissolve anhydrotetracycline hydrochloride?
1 answer-
Anhydrotetracycline hydrochloride can be dissolved in any of several different organic solvents:1. Ethanol: 2 mg/mL2. DMSO: 10 mg/mL3. DMF: 10 mg/mL.
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