234140

Collagenase Inhibitor I

The Collagenase Inhibitor I controls the biological activity of Collagenase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• Synonym(s): Collagenase Inhibitor I, Z-PDLDA-NHOH
• Empirical Formula (Hill Notation): C₂₂H₃₂N₄O₆
• Molecular Weight: 448.51
• UNSPSC Code: 12352200
• NACRES: NA.54

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: solid
• potency: 1 μM IC₅₀
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white
• solubility: ethanol: 5 mg/mL
• shipped in: ambient
• storage temp.: −20°C

Description

General description

A potent and specific inhibitor of vertebrate collagenases with IC₅₀ values in the micromolar range.

A potent and specific inhibitor of vertebrate collagenases with IC₅₀ values in the order of 1 µM.

Biochem/physiol Actions

Cell permeable: no

Primary Target
vertebrate collegenases

Product does not compete with ATP.

Reversible: no

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Sequence

Z-Pro-D-Leu-D-Ala-NHOH

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Odake, S., et al. 1990. Chem. Pharm. Bull. 38, 1007.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable