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348104

Sigma-Aldrich

Triphenyltin hydroxide

Synonym(s):

Fentin hydroxide, Hydroxytriphenylstannane, NSC 113243

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About This Item

Linear Formula:
(C6H5)3SnOH
CAS Number:
Molecular Weight:
367.03
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.22

Quality Level

mp

124-126 °C (lit.)

SMILES string

O[Sn](c1ccccc1)(c2ccccc2)c3ccccc3

InChI

1S/3C6H5.H2O.Sn/c3*1-2-4-6-5-3-1;;/h3*1-5H;1H2;/q;;;;+1/p-1

InChI key

BFWMWWXRWVJXSE-UHFFFAOYSA-M

Application

Reactant involved in transmetalation reactions with Ir clusters

Reactant involved in synthesis of:
  • (E)-(Nitrophenyl)propenoic acid organotin(IV) carboxylates with antitumor activity
  • Triorganotin chrysanthemumates for larvicidal studies
  • Polynuclear organotin(IV) carboxylates containing ferrocenyl moieties for antitumor investigation
  • Organotin(IV) aminophenylacrylate complexes
  • 4-Biphenylcarboxylic acid derivatives for in vitro cytotoxicity studies

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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J G Vos et al.
Toxicology, 29(4), 325-336 (1984-02-01)
To evaluate the functional significance of triphenyltin hydroxide (TPTH)-induced lymphopenia and lymphocyte depletion in thymus-dependent areas of spleen and lymph nodes, various immune function studies were carried out after 3 or 4 weeks TPTH exposure. Weaned male rats were fed
Fungicide residues. Part VII. Determination of residues of fentin in vegetables and cocoa products by spectrofluorimetry.
P G Baker et al.
The Analyst, 105(1248), 282-285 (1980-03-01)
Marcia Sarpa et al.
Journal of toxicology and environmental health. Part A, 73(13-14), 965-971 (2010-06-22)
Fentin or triphenylthin (TPT) is an organotin compound (OTC) widely used as an agricultural fungicide and miticide. It is well known that TPT exerts adverse effects on the reproductive and immune systems and may disrupt the endocrine system, raising concerns
David I Shapiro-Ilan et al.
Environmental entomology, 40(1), 59-65 (2011-12-21)
Hypocreales fungi such as Beauveria bassiana (Balsamo) Vuillemin and Metarhizium brunneum Petch can be negatively affected by fungicides thereby reducing their biocontrol potential. In a previous study, we demonstrated enhanced fungicide resistance in B. bassiana through artificial selection. However, it
G E Walsh et al.
Ecotoxicology and environmental safety, 12(1), 95-100 (1986-08-01)
Effects of water-bourne toxicants on regeneration of arms by the brittle star, Ophioderma brevispina, are described. Regeneration was inhibited by 0.1 micrograms liter-1 bis(tri-n-butyltin)oxide and bis(triphenyltin)oxide. Both substances are known to act upon the nervous system, and it is suggested

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