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173754

Sigma-Aldrich

3,3′-Diethylthiadicarbocyanine iodide

Dye content 98 %

Synonym(s):

3-Ethyl-2-[5-(3-ethyl-2(3H)-benzothiazolylidene)-1,3-pentadienyl]benzothiazolium iodide, DTDCI, DiSC2(5)

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About This Item

Empirical Formula (Hill Notation):
C23H23IN2S2
CAS Number:
514-73-8
Molecular Weight:
518.48
Beilstein:
3838938
EC Number:
208-186-7
MDL number:
MFCD00074829
UNSPSC Code:
12352103
PubChem Substance ID:
24850469
NACRES:
NA.23
Pricing and availability is not currently available.

composition

Dye content, 98%

mp

249 °C (dec.) (lit.)

λmax

655 nm

SMILES string

[I-].CCN1/C(Sc2ccccc12)=C\C=C\C=C\c3sc4ccccc4[n+]3CC

InChI

1S/C23H23N2S2.HI/c1-3-24-18-12-8-10-14-20(18)26-22(24)16-6-5-7-17-23-25(4-2)19-13-9-11-15-21(19)27-23;/h5-17H,3-4H2,1-2H3;1H/q+1;/p-1

InChI key

MNQDKWZEUULFPX-UHFFFAOYSA-M

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Application

DTDCi is used as;
  • Fluorescent contrast agent in three-dimensional fluorescence lifetime tomography.[1]
  • Dye for rapid genetic screening.[2]

Features and Benefits

High quantum yield of photoisomerisation and low triplet quantum yield at direct photoexcitation. Highly sensitive fluorescent dye.[3]

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H300,H315,H319,H335

Hazard Classifications

Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SHBQ3838
SHBQ3632
SHBM4570
MKCJ6490
MKCD3416

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3,3′-Dipropylthiacarbocyanine iodide 98%

Sigma-Aldrich

318434

3,3′-Dipropylthiacarbocyanine iodide

Mengjia Xu et al.
Chembiochem : a European journal of chemical biology, 21(18), 2667-2675 (2020-04-19)
Peptide nucleic acids (PNAs), the synthetic DNA mimics that can bind to oligonucleotides to form duplexes, triplexes, and quadruplexes, could be advantageous as probes for nucleic acid sequences owing to their unique physicochemical and biochemical properties. We have found that
Photophysical processes of polymethine dyes. An absorption, emission, and optoacoustic study on 3, 3'-diethylthiadicarbocyanine iodide.
Bilmes GM, et al.
The Journal of Physical Chemistry, 93(18), 6696-6699 (1989)
Jiang Pi et al.
Materials science & engineering. C, Materials for biological applications, 103, 109777-109777 (2019-07-28)
Tuberculosis (TB), caused by M.tuberculosis (Mtb), has become a top killer among infectious diseases. Enhancing the ability of anti-TB drugs to kill intracellular Mtb in host cells remains a big challenge. Here, an innovative nano-system was developed to increase drug
Ryan M Williams et al.
Hypertension (Dallas, Tex. : 1979), 71(1), 87-94 (2017-11-15)
Direct targeting to the kidneys is a promising strategy to improve drug therapeutic index for the treatment of kidney diseases. We sought to investigate the renal selectivity and safety of kidney-targeted mesoscale nanoparticle technology. We found that direct intravenous administration
L Marcus Wilhelmsson et al.
Nucleic acids research, 30(2), E3-E3 (2002-01-15)
As the relationship between human genes and various malfunctions and diseases becomes revealed at an ever-increasing pace, the need arises for the development of rapid genetic screening methods for diagnostic purposes. Genetic diseases show great diversity. Some are caused by
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Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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