146188
2-Hydroxy-5-methoxybenzoic acid
98%
Synonym(s):
5-Methoxysalicylic acid
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About This Item
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Quality Level
Assay
98%
form
powder
mp
141-143 °C (lit.)
functional group
carboxylic acid
SMILES string
COc1ccc(O)c(c1)C(O)=O
InChI
1S/C8H8O4/c1-12-5-2-3-7(9)6(4-5)8(10)11/h2-4,9H,1H3,(H,10,11)
InChI key
IZZIWIAOVZOBLF-UHFFFAOYSA-N
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General description
2-Hydroxy-5-methoxybenzoic acid is matrix additive which enhances the electrical conductivity of the matrix crystal during matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS).
Application
2-Hydroxy-5-methoxybenzoic acid was used to evaluate MALDI matrix/solvent combinations for intact spore mass spectrometry of Fusarium species.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Rapid communications in mass spectrometry : RCM, 23(6), 877-884 (2009-02-19)
Unambiguous identification of mycotoxin-producing fungal species as Fusarium is of great relevance to agriculture and the food-producing industry as well as in medicine. Protein profiles of intact fungal spores, such as Penicillium, Aspergillus and Trichoderma, derived from matrix-assisted laser desorption/ionization
Journal of experimental botany, 68(21-22), 5801-5811 (2017-12-01)
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High-throughput matrix-assisted laser desorption/ionization mass spectrometry (HT-MALDI-MS) has garnered considerable attention within the drug discovery industry as an information-rich alternative to assays using light-based detection methods. To date, these efforts have been primarily focused on assays using protein or peptide
Molecular & cellular proteomics : MCP, 16(2), 278-287 (2016-12-14)
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The rectal absorption of pepleomycin sulfate (PEPS) in rats was increased significantly by the coadministration with each of diclofenac (DC), sodium 5-methoxysalicylate (5-MSA) and phenylalanine enamine of ethylacetoacetate (Enamine). 5-MSA increased the lymphatic uptake of PEPS after rectal administration while
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