1466674

N-Nitrosodimethylamine (NDMA)

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): N-Methyl-N-nitrosomethanamine, NDMA
• Empirical Formula (Hill Notation): C₂H₆N₂O
• CAS Number: 62-75-9
• Molecular Weight: 74.08
• MDL number: MFCD00002053
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• agency: USP
• form: liquid
• packaging: pkg of 1 mg
• manufacturer/tradename: USP
• application(s): USP Biologics; pharmaceutical (small molecules); pharmaceutical; pharmaceutical
• format: single component solution (solution in methanol)
• storage temp.: −20°C
• SMILES string: N(N=O)(C)C
• InChI: 1S/C2H6N2O/c1-4(2)3-5/h1-2H3
• InChI key: UMFJAHHVKNCGLG-UHFFFAOYSA-N

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

Application

N-Nitrosodimethylamine (NDMA) USP reference standard is intended for use only as specificallyprescribed in the United States Pharmacopoeia.

It is also used to prepare standard, standard stock, nitrosamine RS stock, nitrosamine standards stock solution mixture, and sensitivity stock solutions to determine NDMA impurity in drug substances and drug products(valsartan, irbesartan, and losartan potassium etc.) by chromatography method according to the general chapter 〈1469〉 of United States Pharmacopeia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  

Other Notes

Sales restrictions may apply.

This product is part of USP Biologics Program.

This product is provided as delivered and specified by the USP Pharmacopoeia. For further information and support, including certificate/ product information sheets, please go to the website of the issuing Pharmacopoeia.

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Codes: H225,H301 + H311 + H331,H350,H370
• Precautionary Statements: P201 - P210 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes,Central nervous system
• Storage Class: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point (°F): 49.5 °F
• Flash Point (°C): 9.7 °C