H0396

Hydrocortisone-Water Soluble

BioReagent, suitable for cell culture

• Synonym(s): Cyclodextrin-encapsulated hydrocortisone
• NACRES: NA.77
• PubChem Substance ID: 24895401
• UNSPSC Code: 12352209
• MDL number: MFCD00011654
• Biological source: plant (wild yam)
• Form: crystalline

Properties

• biological source: plant (wild yam)
• Quality Segment: 200
• product line: BioReagent
• form: crystalline
• technique(s): cell culture | mammalian: suitable
• solubility: H₂O: 400 mg/mL
• shipped in: ambient
• storage temp.: room temp
• SMILES string: C[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@](O)(C(=O)CO)[C@@]4(C)C[C@H](O)[C@H]23
• InChI: 1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
• InChI key: JYGXADMDTFJGBT-VWUMJDOOSA-N
• Gene Information: human ... ABCB1(5243), CYP3A4(1576), NR3C1(2908), SERPINA6(866) ; mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126) ; rat ... Ar(24208), Nr3c1(24413)

Description

General description

Hydrocortisone has the potential to induce the formation of blood-brain barrier properties in serum-free culture media. It is recommended for use in epithelial and endothelial adherent cell culture applications.

Application

Hydrocortisone-Water Soluble has been used as a supplement in Dulbecco′s modified Eagle′s medium (DMEM)/high glucose medium to culture mammary alveolar (MAC-T) cells. It has also been used to study its effect on cation absorption by semicircular canal duct epithelium via epithelial sodium channel.

Packaging

Package size based on hydrocortisone

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Codes: H360Df
• Precautionary Statements: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1A
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): dust mask type N95 (US), Eyeshields, Gloves