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F5537

Sigma-Aldrich

Anti-Fibroblast Growth Factor-Basic antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

Anti-FGF2

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About This Item

MDL number:
UNSPSC Code:
51111800
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

dot blot: 1:10,000
neutralization: suitable
radioimmunoassay: 1:10,000
western blot: suitable

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... FGF2(2247)

Specificity

The antibody does not cross-react with recombinant human FGF1, IL-1α, IL-1β, IL-3, or TNF-α, nor with mouse or human IL-6.

Immunogen

recombinant human FGF2 expressed in Escherichia coli.

Physical form

Solution in phosphate buffered saline, 0.2 μm filtered.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A Aigner et al.
International journal of cancer, 92(4), 510-517 (2001-04-17)
Fibroblast growth factors FGF-1 (aFGF) and FGF-2 (bFGF) are found in most embryonic and adult normal and tumor tissues, where they are immobilized in the extracellular matrix (ECM). Mobilization of these FGFs is part of a tightly controlled process resulting
B Spencer et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 3(5 Pt 1), 746-756 (2001-05-18)
Fibroblast growth factor 2 (bFGF, FGF2) exhibits mitogenic, angiogenic, wound healing, and neuroprotective properties. Infusion of FGF2 in vivo to treat neurodegenerative disorders in animal models results in increased survival of damaged neurons, but these effects are transient. To test
Min Qin et al.
American journal of respiratory cell and molecular biology, 32(3), 211-217 (2005-01-01)
We compared native Adenoviral (Ad) vectors to a basic Fibroblast Growth Factor-retargeted Adenovirus (FGF2-Ad) for gene delivery into a diverse panel of lung cancer cells in vitro and xenografts in vivo. Cells were first evaluated for vector-specific receptor expression. Marked
Angiogenic cytokines. Quantitative and functional analysis.
Angelika Eggert et al.
Methods in molecular biology (Clifton, N.J.), 215, 117-133 (2003-01-07)

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