The prepared solution is stable for several months if sterile-filtered and stored at 2-8 °C.
A2786
Adenine
BioReagent, suitable for cell culture
Synonym(s):
6-Aminopurine, Vitamin B4
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About This Item
Empirical Formula (Hill Notation):
C5H5N5
CAS Number:
Molecular Weight:
135.13
UNSPSC Code:
12352205
NACRES:
NA.75
PubChem Substance ID:
EC Number:
200-796-1
Beilstein/REAXYS Number:
5777
MDL number:
Pricing and availability is not currently available.
biological source
synthetic
Quality Segment
product line
BioReagent
assay
≥99%
form
powder
mol wt
Mw 135.13 g/mol
technique(s)
cell culture | mammalian: suitable
color
white to off-white
mp
>360 °C (lit.)
solubility
0.5 M HCl: soluble 20 mg/mL, clear to slightly hazy, colorless to faintly yellow
storage temp.
room temp
SMILES string
Nc1ncnc2[nH]cnc12
InChI
1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)
InChI key
GFFGJBXGBJISGV-UHFFFAOYSA-N
Gene Information
human ... AKT1(207), GSK3B(2932), LCK(3932), MAP3K1(4214), MAPK14(1432), MAPK8(5599), MAPK9(5601), MAPKAPK2(9261), PRKACA(5566), PRKCA(5578), RAF1(5894), ROCK2(9475)
mouse ... Mapk1(26413)
rat ... Camk2a(25400), Mapk10(25272)
General description
Adenine is a purine nucleobase, synthesized from inosine monophosphate(IMP). It is a nitrogenous heterocyclic aromatic compound.
Application
Adenine has been used:
- a component of green medium used for the derivation of keratinocytes from plucked hair follicles
- for the serial culture of adult murine keratinocytes
- as a media component for SSEA4+ limbal stromal stem cell differentiation
Biochem/physiol Actions
Adenine is a component of important biomolecules such as adenosine triphosphate (ATP), nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD). NAD and FAD forms the structure of DNA and RNA, and plays important role in protein synthesis. ATP is an energy source, that is essential for cellular respiration.
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This Item | |||
|---|---|---|---|
| form powder | form powder | form - | form powder |
| technique(s) cell culture | mammalian: suitable | technique(s) cell culture | plant: suitable | technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) UV/Vis spectroscopy: suitable |
| biological source synthetic | biological source - | biological source - | biological source synthetic |
| storage temp. room temp | storage temp. - | storage temp. 2-8°C | storage temp. room temp |
| solubility 0.5 M HCl: soluble 20 mg/mL, clear to slightly hazy, colorless to faintly yellow | solubility 0.5 M HCl: soluble 20 mg/mL, clear to slightly hazy, colorless to faintly yellow | solubility - | solubility 0.5 M HCl: soluble 20 mg/mL, Grade III, colorless to faint yellow or tan |
| Quality Level 200 | Quality Level 200 | Quality Level 300 | Quality Level 200 |
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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When reconstitute in 0.5M HCl, where the solution should be stored?
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