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D4911

Sigma-Aldrich

Dextran sulfate sodium salt from Leuconostoc spp.

mol wt 6,500-10,000

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.21

biological source

bacterial (Leuconostoc)

Quality Level

form

powder

mol wt

6,500-10,000

composition

Sulfur Content, 16.0-22.0%

color

white to light yellow

useful pH range

6.0-8 (10 g/L)

solubility

H2O: 100 mg/mL

storage temp.

room temp

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General description

Dextran sulfate is a sulfated polysaccharide, which is negatively charged. It is produced by the esterification of dextran with chlorosulphonic acid. Dextran is used to treat hemorrhage, burns, surgery and trauma. It improves blood flow and prevents erythrocyte aggregation. Dextran lowers the risk of thrombosis and postoperative pulmonary emboli. It is a ribonuclease inhibitor. Dextran sulfate exhibits antiviral, anticoagulant and adjuvant properties.

Application

Dextran sulfate sodium salt Leuconostoc spp has been used:
  • as a standard to perform polyacrylamide-gel electrophoresis for carbohydrates (C-PAGE)(59) and agarose gel electrophoresis(60)
  • for RNA sequential probing of targets (SPOTs) imaging(61)
  • as a component of 1% injection buffer(62)

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Valter R M Lombardi et al.
Journal of biomedicine & biotechnology, 2012, 826178-826178 (2012-05-24)
One of the main treatments currently used in humans to fight cancer is chemotherapy. A huge number of compounds with antitumor activity are present in nature, and many of their derivatives are produced by microorganisms. However, the search for new
The Molecular Biology of Poliovirus (2012)
The Molecular Biology of Poliovirus (2012)
Radiotherapy, Surgery, and Immunotherapy (2012)
Rheology of Industrial Polysaccharides: Theory and Applications (2012)

Protocols

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Related Content

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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