8.22252

Acetyl chloride

for synthesis

• Synonym(s): Acetyl chloride, Acetic acid chloride, Acetoxy chloride
• Empirical Formula (Hill Notation): C₂H₃ClO
• CAS Number: 75-36-5
• Molecular Weight: 78.50
• MDL number: MFCD00000719
• UNSPSC Code: 12352106
• EC Index Number: 200-865-6
• NACRES: NA.22

Properties

• vapor pressure: 320 hPa ( 20 °C)
• Quality Level: 200
• form: liquid
• autoignition temp.: 390 °C (DIN 51794)
• expl. lim.: 7.3-19 % (v/v)
• bp: 52 °C/1013 hPa
• mp: -112 °C
• transition temp: flash point 5 °C
• density: 1.10 g/cm³ at 20 °C
• storage temp.: 2-30°C
• SMILES string: ClC(=O)C
• InChI: 1S/C2H3ClO/c1-2(3)4/h1H3
• InChI key: WETWJCDKMRHUPV-UHFFFAOYSA-N

Description

Application

• Acetyl chloride in nano-electrospray ionization: Acetyl chloride is utilized for consecutive-ionization of cholesterol in nano-electrospray mass spectrometry, enhancing lipid analysis capabilities (Foest et al., 2023).
• Acetyl chloride in live-cell imaging: A study details the use of acetyl chloride in developing a coumarin-based fluorescent probe for ratiometric detection of hydrazine, applicable in live cell imaging (Qu et al., 2019).
• Acetyl chloride in archaeological preservation: Acetyl chloride is applied in the chemical characterization of archaeological wood, providing insights into the conservation of historical artifacts (Zoia et al., 2017).

Analysis Note

Assay (morpholine method): ≥ 98.0 %
Density (d 5°C/ 4°C): 1.127 - 1.129
Identity (IR): passes test

Safety Information

• Pictograms: GHS02,GHS05
• Signal Word: Danger
• Hazard Statements: H225 - H314
• Precautionary Statements: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
• Supplementary Hazards: EUH014
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 41.0 °F
• Flash Point(C): 5 °C