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Sigma-Aldrich

Kallikrein, Human Plasma

Native Kallikrein from human plasma. A serine protease that releases bradykinin from kininogen. Present in the plasma as an inactive precursor, prokallikrein.

Synonym(s):

Kallikrein, Human Plasma, Kininogenin, Kininogenase

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About This Item

CAS Number:
Enzyme Commission number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.77

biological source

human plasma

Quality Level

Assay

≥95% (SDS-PAGE)

form

liquid

specific activity

≥15 units/mg protein

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

storage temp.

−20°C

General description

Native Kallikrein from human plasma. A serine protease that releases bradykinin from kininogen. Present in the plasma as an active precursor, prokallikrein.
Native Kallikrein from human plasma. A serine protease that releases bradykinin from kininogen. Present in the plasma as an inactive precursor, prokallikrein.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Harmful (C)

Unit Definition

One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol D-Pro-Phe-Arg-pNA per min at 25°C, pH 8.0.

Physical form

In NaCl and Tris-HCl buffer.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Pu, X., et al. 1994. Biochim. Biophys. Acta 1208, 338.
Nagase, H. and Barrett, A.J. 1981. Biochem. J.193, 187.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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