The molecular weight of Product 407709 Insulin, Zinc, Human, Recombinant, is 5807 Da. Purity is 99.2 % pure by HPLC, < 10.0 EnU/mg, and Potency of 28.5 IU/mg.
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About This Item
Biological source:
yeast (Pichia pastoris)
Form:
solid
Assay:
≥95—105%
Pricing and availability is not currently available.
biological source
yeast (Pichia pastoris)
Quality Level
description
Merck USA index - 14, 4980
sterility
non-sterile
assay
≥95—105%
form
solid
specific activity
≥25 IU/mg (dry basis)
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
<10 EU/mg Endotoxin (EU/mg protein)
color
white to off-white
solubility
0.01 M HCl: soluble
shipped in
wet ice
storage temp.
−20°C
InChI key
PBGKTOXHQIOBKM-FHFVDXKLSA-N
General description
Recombinant, human insulin (zinc) expressed in P. pastoris. Peptide anabolic hormone produced by pancreatic β-cells. Increases the synthesis of protein, fat, glycogen, and substrate oxidation in mitochondria. Interacts with membrane insulin receptor to cause its biological actions.
Preparation Note
Following reconstitution store in the refrigerator (4°C). Stock solutions are stable for up to 6 weeks at 4°C.
Insulin is practically insoluble from pH 4.5-7.0.
Other Notes
Mohan, C., et al. 1989. Curr. Topics Cell. Reg.30, 105.
Johnson, I.S. 1983. Science219, 632.
Johnson, I.S. 1983. Science219, 632.
≥25 IU/mg (dry basis).
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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This Item | |||
|---|---|---|---|
| biological source yeast (Pichia pastoris) | biological source - | biological source Saccharomyces cerevisiae | biological source - |
| assay ≥95—105% | assay >98% (SDS-PAGE) | assay - | assay - |
| Quality Level 200 | Quality Level - | Quality Level 200 | Quality Level - |
| form solid | form lyophilized (clear, colorless solution after reconstitution) | form lyophilized powder | form solid |
| storage condition OK to freeze | storage condition - | storage condition - | storage condition - |
| shipped in wet ice | shipped in - | shipped in ambient | shipped in - |
Storage Class
11 - Combustible Solids
wgk
nwg
Certificates of Analysis (COA)
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Mohan Sreelekshmi et al.
Journal of biochemical and molecular toxicology, 35(6), 1-8 (2021-03-03)
Glucokinase (GK), a key regulator of hepatic glucose metabolism in the liver and glucose sensor and mediator in the secretion of insulin in the pancreas, is not studied in detail for its therapeutic application in diabetes. Herein, we study the
Kapil Manglani et al.
Cell biology international, 46(3), 488-497 (2021-12-06)
Role of CDK5 and its inhibition in various neuronal processes and functions are well established. However, role of CDK5 and its inhibition in neuronal insulin-signaling and-resistance is not yet explored. In the present study, we investigated the effect of CDK5
Medha Sharma et al.
Cell communication and signaling : CCS, 20(1), 179-179 (2022-11-16)
The aim of the present study was to determine the role of individual PHLPP isoforms in insulin signaling and insulin resistance in neuronal cells. PHLPP isoforms were either silenced or overexpressed individually, and the effects were observed on individual Akt
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 407709-50MG | 07790788050047 |
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