929638

Poly(ethylene glycol) diacrylamide

M_n 3400, contains MEHQ as stabilizer

• Synonym(s): PEG diacrylamide, PEG hydrogel, PEGDAAm
• Linear Formula: H₂CCHC(O)NH(CH₂CH₂O)_n CH₂CH₂NHC(O)CHCH₂
• CAS Number: 160556-48-9
• UNSPSC Code: 12191502
• NACRES: NA.25

Properties

• form: fine powder
• Quality Level: 100
• mol wt: M_n 3400; average M_n 3400
• contains: ≥25 ppm MEHQ as inhibitor; MEHQ as stabilizer
• color: white to off-white
• solubility: deionized water: 20 wt. % at 23 °C
• Ω-end: acrylamide
• α-end: acrylamide
• storage temp.: −20°C

Description

General description

Poly(ethylene glycol) (PEG) diacrylamide is a linear, homobifunctional crosslinking PEG polymer with two acrylamide groups. PEG diacrylamide replaces the unstable ester bonds of commonly used PEG diacrylate crosslinkers with hydrolytically stable amides.

Application

PEG diacrylamide is a biocompatible, hydrophilic polymer commonly used to form crosslinked polymer networks and PEG hydrogels. Crosslinked networks can be formed via radical initiator induced polymerization and photopolymerization. Due to its stable amide bond, PEG dacrylamide can be used to prepare hydrogels suitable for long-term studies and eliminate non-specific hydrogel degradation. The acrylamide functional groups can also be reacted with thiol-containing peptide crosslinkers to create enzymatically-sensitive crosslinked networks. PEG diacrylamide has numerous applications in tissue engineering, 3D printing, and drug delivery.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable