Skip to Content
Merck
All Photos(5)

Key Documents

R3875

Sigma-Aldrich

L-Rhamnose monohydrate

≥99%

Synonym(s):

6-Deoxy-L-mannose, L(+)Rhamnopyranose

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C6H12O5 · H2O
CAS Number:
Molecular Weight:
182.17
Beilstein:
3912643
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

biological source

oranges

Quality Level

Assay

≥99%

form

powder

technique(s)

gas chromatography (GC): suitable

color

white to off-white

mp

90 °C

solubility

water: 50 mg/mL, clear, colorless

storage temp.

room temp

SMILES string

O.C[C@@H]1O[C@@H](O)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C6H12O5.H2O/c1-2-3(7)4(8)5(9)6(10)11-2;/h2-10H,1H3;1H2/t2-,3-,4+,5+,6+;/m0./s1

InChI key

BNRKZHXOBMEUGK-NRBMBCGPSA-N

Looking for similar products? Visit Product Comparison Guide

General description

L-Rhamnose is a part of plant cell wall polysaccharides, rhamnogalacturonan I and rhamnogalacturonan. It is also present in bacterial cell walland a major antigenic determinant contributing to its pathogenicity. L-rhamnose is non-absorbable in humans but is fermented by intestinal microbes. Supplementation of L-rhamnose slows down gastric emptying. L-rhamnose monosaccharide conjugated immunogens have applications in cancer immunotherapies. Intake of L-rhamnose elevates serum propionate levels.

Application

L-Rhamnose monohydrate has been used:
  • in biofilm enhancement assay in S.pneumonia
  • as a sugar drink in humans undergoing intestinal barrier permeability test
  • for the standard curve generation in high performance liquid chromatography(HPLC)

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

The effect of L-rhamnose on intestinal transit time, short chain fatty acids and appetite regulation: a pilot human study using combined 13CO2/H2 breath tests
Byrne CS, et al.
Journal of Breath Research, 12(4), 046006-046006 (2018)
L-Rhamnose increases serum propionate in humans
Vogt JA, et al.
American Journal of Clinical Nutrition, 80(1), 89-94 (2004)
L-Rhamnose induction of Aspergillus alpha-L-rhamnosidase genes is glucose repressed via a CreA-independent mechanism acting at the level of inducer uptake
Tamayo-Ramos JA, et al.
Microbial cell factories, 11(1), 26-26 (2012)
Bacterial glycobiology: rhamnose-containing cell wall polysaccharides in Gram-positive bacteria
Mistou MY, et al.
FEMS Microbiology Reviews, 40(4), 464-479 (2016)
L-rhamnose antigen: a promising alternative to alpha-gal for cancer immunotherapies
Chen W, et al.
ACS Chemical Biology, 6(2), 185-191 (2010)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service