O2751
Sodium oxamate
≥98%
Synonym(s):
Aminooxoacetic acid sodium salt, Oxalic acid monoamide sodium salt, Oxamic acid sodium salt
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About This Item
Linear Formula:
NH2COCOONa
CAS Number:
Molecular Weight:
111.03
Beilstein:
6538153
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77
Recommended Products
biological source
synthetic (organic)
Quality Level
Assay
≥98%
form
powder
mp
300 °C
solubility
water: 50 mg/mL, clear, colorless
SMILES string
[Na+].NC(=O)C([O-])=O
InChI
1S/C2H3NO3.Na/c3-1(4)2(5)6;/h(H2,3,4)(H,5,6);/q;+1/p-1
InChI key
RQVZIJIQDCGIKI-UHFFFAOYSA-M
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Application
Sodium oxamate has been used:
- as one of the variable in flow injection analysis
- in in vitro angiogenesis assay
- to confirm the stimulatory role of stearic acid on lactate dehydrogenase mediated lactate production
Biochem/physiol Actions
Sodium oxamate influences the fatty acid metabolism. It might be useful for the treatment of diabetes.
Structural analog of pyruvate, inhibits L(+)-lactate dehydrogenase and derails the entire gluconeogenic pathway. Binding studies with lactate dehydrogenase; Mechanism of inhibition of mitochondrial pyruvate metabolism
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Fluorescence of Reduced Nicotinamide Adenine Dinucleotide (NADH) is extensively employed in studies of oxidoreductases. A substantial amount of static and kinetic work has focused on the binding of pyruvate or substrate mimic oxamate to the binary complex of lactate dehydrogenase
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