H7891
Hexammine cobalt(III) chloride
for use in transformations, X-ray crystallography and NMR
Synonym(s):
Cobalt hexammine trichloride, Hexaamminecobalt trichloride
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About This Item
Linear Formula:
[Co(NH3)6]Cl3
CAS Number:
Molecular Weight:
267.48
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.52
Recommended Products
grade
for molecular biology
Quality Level
form
powder
storage temp.
room temp
SMILES string
N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Co+3]
InChI
1S/3ClH.Co.6H3N/h3*1H;;6*1H3/q;;;+3;;;;;;/p-3
InChI key
JXBGZYGSWFSYFI-UHFFFAOYSA-K
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General description
Hexammine cobalt(III) is considered an analog of fully solvated magnesium, capable of activating some enzymes that requires magnesium. It is useful in DNA condensation studies.
Application
Suitable for
- DNA condensation studies
- induction of transitions of DNA from B to A or Z forms
- induction of nucleic acid crystal growth
- stabilization of tertiary tRNA interactions
- preparation of ligation buffer
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Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 4 - Carc. 2 - Resp. Sens. 1 - Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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These studies employed the synthetic linear DNA, poly dGdC, in the B and cobalt hexammine chloride (Co)-induced Z form to determine the effect of conformation on protein-DNA interactions. The rate of the reaction of the restriction endonucleases, Hha I and
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