490733
Sodium pyruvate-3-13C
99 atom % 13C
Synonym(s):
Pyruvic acid-3-13C sodium salt
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About This Item
Linear Formula:
13CH3COCO2Na
CAS Number:
Molecular Weight:
111.04
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.12
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isotopic purity
99 atom % 13C
Quality Level
Assay
99% (CP)
form
solid
technique(s)
bio NMR: suitable
mass spectrometry (MS): suitable
mp
>300 °C (lit.)
mass shift
M+1
storage temp.
2-8°C
SMILES string
[Na+].[13CH3]C(=O)C([O-])=O
InChI
1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1/i1+1;
InChI key
DAEPDZWVDSPTHF-YTBWXGASSA-M
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General description
Sodium pyruvate-3-13C is an isotopic analogue of sodium pyruvate.
Application
Sodium pyruvate-3-13C is used to study the brain metabolism of exogenous pyruvate.It is also used to investigate the pyruvate metabolism in living cancer cells.
Packaging
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Sens. 1B
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Susana Villa Gonzalez et al.
Journal of neurochemistry, 95(1), 284-293 (2005-09-27)
Pyruvate given in large doses may be neuroprotective in stroke, but it is not known to what degree the brain metabolizes pyruvate. Intravenous injection of [3-13C]pyruvate led to dose-dependent labelling of cerebral metabolites so that at 5 min after injection
Chendong Yang et al.
The Journal of biological chemistry, 289(9), 6212-6224 (2014-01-15)
Metabolic reprogramming facilitates cancer cell growth, so quantitative metabolic flux measurements could produce useful biomarkers. However, current methods to analyze flux in vivo provide either a steady-state overview of relative activities (infusion of (13)C and analysis of extracted metabolites) or
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