453188
D-Glucose-1,2-13C2
99 atom % 13C
Synonym(s):
Labeled Glucose, Dextrose-1,2-13C2
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All Photos(3)
About This Item
Empirical Formula (Hill Notation):
13C2C4H12O6
CAS Number:
Molecular Weight:
182.14
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.12
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isotopic purity
99 atom % 13C
Quality Level
Assay
99% (CP)
form
powder
optical activity
[α]25/D +52.0°, c = 2 in H2O (trace NH4OH)
mp
150-152 °C (lit.)
mass shift
M+2
SMILES string
OC[C@@H](O)[C@@H](O)[C@H](O)[13C@@H](O)[13CH]=O
InChI
1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6+/m0/s1/i1+1,3+1
InChI key
GZCGUPFRVQAUEE-SZEFTZBMSA-N
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Application
D-Glucose-1,2-13C2 can be used:
- As a stable isotope in the in vivo study of dynamic metabolic profiling of pancreatic tumor.
- To study the nonoxidative pentose phosphate pathway using a single-tracer method.
Packaging
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Mass isotopomer study of the nonoxidative pathways of the pentose cycle with [1, 2-13C2] glucose
Lee, WP, et al.
American Journal of Physiology. Endocrinology and Metabolism, 274(5), E843-E851 (1998)
[1, 2-13C2]-D-glucose profiles of the serum, liver, pancreas, and DMBA-induced pancreatic tumors of rats
Boros L, et al.
Pancreas, 31(4), 337-343 (2005)
Joanna L Gillis et al.
eLife, 10 (2021-08-13)
Alterations to the androgen receptor (AR) signalling axis and cellular metabolism are hallmarks of prostate cancer. This study provides insight into both hallmarks by uncovering a novel link between AR and the pentose phosphate pathway (PPP). Specifically, we identify 6-phosphogluoconate
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