Skip to Content
Merck
All Photos(1)

Key Documents

L3262

Sigma-Aldrich

Anti-Lactoferrin antibody produced in rabbit

fractionated antiserum, lyophilized powder

Synonym(s):

Anti-Draculin, Anti-Draculin-1

Sign Into View Organizational & Contract Pricing


About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

fractionated antiserum

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human

packaging

vial of 2 mL lyophilized antiserum

technique(s)

direct ELISA: 1:10,000 using using human lactoferrin

UniProt accession no.

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... LTF(4057)

General description

Lactoferrin, globular glycoprotein belongs to transferrin protein family. It is mapped to human chromosome 3p21.31. Lactoferrin comprises 692 amino acids with two globular lobes linked by α-helix and belongs to transferrin family. It exists in three isoforms namely lactoferrin-α, lactoferrin-γ, and lactoferrin-β. Lactoferrin corresponds to a molecular weight of 80 kDa.

Specificity

Rabbit polyclonal anti-lactoferrin antibody reacts with purified lactoferrin and human milk, but does not react with human serum proteins.

Application

Anti-Lactoferrin antibody produced in rabbit has been used in:
  • western blotting
  • indirect immunofluorescence
  • flow cytometry
  • enzyme-linked immunosorbent assay (ELISA)

Biochem/physiol Actions

A primary function of lactoferrin is to bind and transport iron ions. However, lactoferrin is also an effective antibacterial, antiviral, antiparasitic, catalytic (RNA degrading), anti-cancer molecule. It elicits anti-inflammatory effects in asthma. It has immunomodulatory and anti-inflammatory functionality and is a potential protein nutraceutical.

Physical form

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2

Reconstitution

Reconstitute with 2 ml deionized water.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Functional fragments of ingested lactoferrin are resistant to proteolytic degradation in the gastrointestinal tract of adult rats
Kuwata H, et al.
The Journal of Nutrition, 131(8), 2121-2127 (2001)
Lulu Hu et al.
Bioscience, biotechnology, and biochemistry, 80(2), 257-263 (2015-09-26)
Lactoferrin (LTF), a multifunctional glycoprotein of the transferrin family mainly found in exotic secretions in mammals, is an important defense molecule against not only microbial invasion but also tumors. It folds into two globular domains (N- and C-lobes) each containing
Unstimulated salivary flow, pH, proteins and oral health in patients with Juvenile Idiopathic Arthritis
Kobus A, et al.
BMC Oral Health, 17(1), 94-94 (2017)
Rachita Panda et al.
Frontiers in immunology, 8, 439-439 (2017-04-30)
Neutrophil extracellular traps (NETs) are chromatin filaments decorated with enzymes from neutrophil cytoplasmic granules. Anti-neutrophil cytoplasmic antibodies (ANCAs) bind to enzymes from neutrophil cytoplasmic granules and are biomarkers for the diagnosis of systemic vasculitides. ANCA diagnostics are based on indirect
Expression, purification, and breast cancer cell inhibiting effect of recombinant human lactoferrin C-lobe
Hu L, et al.
Bioscience, Biotechnology, and Biochemistry, 80(2), 257-263 (2016)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service