H9903
1-(Heptafluorobutyryl)imidazole
BioReagent, suitable for derivatization
Synonym(s):
1-(Perfluorobutyryl)imidazole
Sign Into View Organizational & Contract Pricing
All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C7H3F7N2O
CAS Number:
Molecular Weight:
264.10
Beilstein:
4488026
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.32
Recommended Products
product line
BioReagent
Quality Level
bp
158-163 °C (lit.)
suitability
suitable for derivatization
storage temp.
−20°C
SMILES string
FC(F)(F)C(F)(F)C(F)(F)C(=O)n1ccnc1
InChI
1S/C7H3F7N2O/c8-5(9,6(10,11)7(12,13)14)4(17)16-2-1-15-3-16/h1-3H
InChI key
MSYHGYDAVLDKCE-UHFFFAOYSA-N
Looking for similar products? Visit Product Comparison Guide
General description
1-(Heptafluorobutyryl)imidazole, also known as HFBI, is an acylating derivatization reagent. It is a mild amine-group derivatizing agent. HFBI doesn’t produce acidic by-products in reaction, and the unutilized reagent doesn’t damage the chromatographic process. Post derivatization reaction, the HFB (Heptafluorobutyryl) derivatives are analyzed chromatographically.
Application
1-(Heptafluorobutyryl)imidazole is used as a derivatizing agent for analysing Sulphur mustard metabolites. It is suitable to study dispersive derivatization of degradation products.
Biochem/physiol Actions
Mild amine-group derivatizing reagent; non-acidic by-product prevents decomposition and reduces GC column degradation.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
170.6 °F - closed cup
Flash Point(C)
77 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Meehir Palit et al.
Journal of chromatography. A, 1218(32), 5393-5400 (2011-07-09)
A new derivatization and extraction technique termed as dispersive derivatization liquid-liquid extraction (DDLLE) speeds up the analysis process by removing the requirement for drying of the sample. The derivatization process takes place at the interface between the analyte containing aqueous
Zhiyong Nie et al.
Talanta, 85(2), 1154-1159 (2011-07-06)
The N-terminal valine adduct (HETE-Val) in globin is believed to behave as a long-lived biomarker after exposure to sulfur mustard (HD). Development of a highly sensitive method for monitoring HETE-Val, particularly at low HD exposure levels or for retrospective detection
Y Luo et al.
Journal of chromatography. B, Biomedical applications, 667(2), 344-348 (1995-05-19)
A method for the monitoring of dihydroetorphine hydrochloride, a powerful anaesthetic and analgesic drug, in biological fluids was developed, involving GC-MS with multiple selected-ion monitoring. Dihydroetorphine was extracted from human blood and urine with dichloromethane and then derivatized with N-heptafluorobutyrylimidazole
A Fidder et al.
Archives of toxicology, 74(4-5), 207-214 (2000-08-26)
The development of a procedure for retrospective detection and quantitation of exposure to the arsenical dichloro(2-chlorovinyl)arsine (lewisite; L1) has been initiated. Upon incubation of human blood with [14C]L1 (20 nM-0.2 mM) in vitro, more than 90% of the total radioactivity
Xinxin Li et al.
Colloids and surfaces. B, Biointerfaces, 74(1), 370-374 (2009-09-01)
Patterning of neural stem cells (NSCs) is of great importance for its potential applications in the therapy of nerve injuries. Due to the critical requirements and the great difficulty in NSCs cultivation, developing new methods for NSCs patterning is very
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service