Skip to Content
Merck
All Photos(1)

Key Documents

5.06135

Sigma-Aldrich

Venlafaxine Hydrochloride

Synonym(s):

Venlafaxine Hydrochloride, SERT/NET Inhibitor, Venlafaxine, Serotonin-norepinephrine Inhibitor, Venlafaxien

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C17H27NO2 · xHCl
CAS Number:
Molecular Weight:
277.40 (free base basis)
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

Assay

≥99% (HPLC)

Quality Level

form

solid

potency

82 nM Ki

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

white

solubility

water: 100 mM
DMSO: 50 mM

storage temp.

2-8°C

InChI

1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H

InChI key

QYRYFNHXARDNFZ-UHFFFAOYSA-N

General description

A dual reuptake inhibitor of serotonin-norepinephrine with strong preference to serotonin (Ki = 82 and 2480 nM for SERT and NET respectively). Also inhibits reuptake of dopamine. Used in studies of depression, ADHD, and stress-related anxiety.

Biochem/physiol Actions

Primary Target
SERT/NET

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Other Notes

Kaur, J., et al. et al. 2010. J. Pharmacy & Bioallied Sci.2, 22.

Aboelwafa, A., et al. 2010. AAPS PharmSciTech.11, 1026.
Bernardi, S., et al. 2009. J. Thermal Analysis & Calorimetry.97, 729.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Environment

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service