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Sigma-Aldrich

Poly(2-hydroxyethyl methacrylate)

average Mv 20,000

Synonym(s):

Poly(2-HEMA), Poly-HEMA

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About This Item

Linear Formula:
(C6H10O3)n
CAS Number:
25249-16-5
MDL number:
MFCD00084374
UNSPSC Code:
12162002
PubChem Substance ID:
24877667
NACRES:
NA.23

form

powder

mol wt

average Mv 20,000

transition temp

Tg 84.8 °C

density

1.15 g/mL at 25 °C (lit.)

SMILES string

CC(=C)C(=O)OCCO

InChI

1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3

InChI key

WOBHKFSMXKNTIM-UHFFFAOYSA-N

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Application

  • Hydrogen-bonds structure in poly(2-hydroxyethyl methacrylate) studied by temperature-dependent infrared spectroscopy: Investigates the hydrogen-bond structure in poly(2-hydroxyethyl methacrylate) (PHEMA) using temperature-dependent IR spectroscopy. (S Morita, 2014).
  • Transparent and tough poly(2-hydroxyethyl methacrylate) hydrogels prepared in water/IL mixtures: Describes the development of tough and transparent PHEMA hydrogels for potential use in various biomedical applications. (Y Liu et al., 2020).
  • Reduced cell attachment to poly(2-hydroxyethyl methacrylate)-coated ventricular catheters in vitro: Examines how PHEMA coatings can reduce cell attachment, which is beneficial for biomedical devices like catheters. (BW Hanak et al., 2018).
  • Surface modification of poly(2-hydroxyethyl methacrylate) hydrogel for contact lens application: Studies modifications to PHEMA hydrogels to improve their suitability for contact lens applications. (M Kazemi Ashtiani, M Zandi, 2018).

Physical form

Water-swellable polymer. Hydrogel.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Amit D Bhrany et al.
JAMA facial plastic surgery, 15(1), 29-33 (2013-01-19)
To evaluate the performance of a sphere-templated poly(2-hydroxyethyl methacrylate) (poly[HEMA]) tissue scaffold as a subcutaneous implant by comparing it with widely used high-density porous polyethylene (HDPPE) implant material. We implanted sphere-templated porous poly-(HEMA) and HDPPE disks into the dorsal subcutis
Yunfeng Li et al.
ACS applied materials & interfaces, 5(6), 2126-2132 (2013-02-23)
This paper presents a versatile way to prepare multiscale and gradient patterns of proteins. The protein patterns are fabricated by conjugating proteins covalently on patterns of polymer brush that are prepared by techniques combining colloidal lithography with photolithography, and two-step
N Nogueira et al.
Journal of colloid and interface science, 385(1), 202-210 (2012-07-31)
The behavior of poly(2-hydroxyethyl methacrylate) (PHEMA) polymer monolayer spread on water was studied under various experimental conditions. The influence of subphase pH and temperature, compression speed, elapsed time from the deposit of the monolayer and the recording of the surface
Olga Samsonova et al.
Acta biomaterialia, 9(2), 4994-5002 (2012-10-13)
The mechanism causing variability in DNA transfection efficacy for low-molecular-weight pDMAEMA (poly(2-(dimethylamino)ethyl methacrylate) and pDMAEMA-b-pHEMA (poly(2-(dimethyl amino)ethylmethacrylate)-block-poly(2-hydroxyl methacrylate)) has so far remained unclear, apart from the evidence of beneficial effects of the pHEMA grafting. This study has explicitly characterized the
Damla Cetin et al.
Journal of materials science. Materials in medicine, 23(11), 2803-2812 (2012-08-09)
The effectiveness of poly(2-hydroxyethyl methacrylate)-gelatin superporous hydrogels (pHEMA-gelatin SPHs) was investigated for bone tissue engineering. The cell culture studies were performed with preosteoblastic MC3T3-E1 cells. Dynamic culture conditions were provided using 100 ml spinner flask rotating at 50 rpm. According
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