254916
7,8-Dihydroxy-6-methoxycoumarin
98%
Synonym(s):
Fraxetin
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About This Item
Empirical Formula (Hill Notation):
C10H8O5
CAS Number:
Molecular Weight:
208.17
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
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Assay
98%
form
powder
mp
230-231 °C (lit.)
SMILES string
COc1cc2C=CC(=O)Oc2c(O)c1O
InChI
1S/C10H8O5/c1-14-6-4-5-2-3-7(11)15-10(5)9(13)8(6)12/h2-4,12-13H,1H3
InChI key
HAVWRBANWNTOJX-UHFFFAOYSA-N
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General description
7,8-Dihydroxy-6-methoxycoumarin is a versatile compound known for its unique fluorescence properties and its role as a photoinitiator in polymerization processes. It exhibits high reactivity under UV light, making it an ideal candidate for applications in the polymerization industry, particularly in the formulation of coatings, adhesives, and inks. It is also used in biomedical applications, such as drug delivery due to its biocompatibility.
Application
7,8-Dihydroxy-6-methoxycoumarincan be used as a UV absorber in polymer formulations. Its ability to absorbultraviolet light helps in protecting polymers from degradation caused by UVradiation, thereby improving their longevity and stability.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Po-Lin Kuo et al.
International immunopharmacology, 6(7), 1167-1175 (2006-05-23)
The survival of osteoblast cells is one of the determinants of the development of osteoporosis in patients with inflamed synovium, such as in rheumatoid arthritis (RA). By means of alkaline phosphatase (ALP) activity and osteocalcin ELISA assay, we have shown
Joana Terés et al.
Plant, cell & environment, 42(8), 2384-2398 (2019-04-25)
High soil carbonate limits crop performance especially in semiarid or arid climates. To understand how plants adapt to such soils, we explored natural variation in tolerance to soil carbonate in small local populations (demes) of Arabidopsis thaliana growing on soils
S Martín-Aragón et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 52(1-2), 55-59 (1997-01-01)
We have evaluated the effects of an oral treatment of mice with fraxetin (25 mg/kg for 30 days) on the glutathione system (GSH, GSSG, and GSSG/GSH ratio as stress index), glutathione reductase (GR) and glutathione peroxidase (GPx) in liver supernatants
Phuong Thien Thuong et al.
Biological & pharmaceutical bulletin, 32(9), 1527-1532 (2009-09-02)
Atherosclerosis is main cause of arteriosclerosis. The pivotal role of low-density lipoprotein (LDL) oxidation in atherogenesis suggests antioxidants may help prevent cardiovascular disease. Fraxinus rhynchophylla DENCE (Oleaceae) is a traditional medicinal plant from East Asia. During the course of characterizing
B Fernandez-Puntero et al.
Biological & pharmaceutical bulletin, 24(7), 777-784 (2001-07-18)
The aim of this paper was to study the influence of Fraxetin (7,8-dihydroxy-6-methoxv coumarin) treatment in a Drosophila melanogaster experimental model, analyzing several parameters in normal situations and instances of induced oxidative stress. Fraxetin treatment was introduced at different ages.
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