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Sigma-Aldrich

1,4-Butanediol diglycidyl ether

technical grade, 60%

Synonym(s):

1,4-Bis(2,3-epoxypropoxy)butane, 1,4-Bis(glycidyloxy)butane, 1,4-Bis(oxiran-2-ylmethoxy)butane, 1,4-Butylene glycol diglycidyl ether, Tetramethylene glycol diglycidyl ether

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About This Item

Empirical Formula (Hill Notation):
C10H18O4
CAS Number:
Molecular Weight:
202.25
Beilstein:
115238
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

grade

technical grade

vapor pressure

~10 mmHg ( 20 °C)

form

liquid

concentration

60%

refractive index

n20/D 1.453 (lit.)

bp

266 °C (lit.)

density

1.1 g/mL at 25 °C (lit.)

SMILES string

C(CCOCC1CO1)COCC2CO2

InChI

1S/C10H18O4/c1(3-11-5-9-7-13-9)2-4-12-6-10-8-14-10/h9-10H,1-8H2

InChI key

SHKUUQIDMUMQQK-UHFFFAOYSA-N

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General description

1,4-Butanediol diglycidyl ether(BDDE) is a homobifunctional monomer with two epoxide groups, widely used to modify the viscosity of epoxy resins. It is also used as a cross-linking agent to synthesize polymer networks.

Application

1,4-Butanediol diglycidyl ether can be used:
  • As a cross-linking agent to prepare hyaluronic acid dermal fillers This crosslinking process enhances the gel-like consistency of the filler, making it more durable and longer-lasting.
  • As a monomer to prepare epoxy-based graphene nanocomposites that have potential applications in the field of flexible electronics, corrosion resistance coatings, and conductive adhesives. BDDE is chosen for its desirable properties such as low viscosity, good reactivity, and compatibility with graphene.

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Comparative physicochemical analysis among 1, 4-butanediol diglycidyl ether cross-linked hyaluronic acid dermal fillers
Nicola Zerbinati, et al.
Gels, 7, 139-139 (2021)
The new face of fillers: why evidence and experience both count.
Hema Sundaram
Journal of drugs in dermatology : JDD, 10(9), 964-964 (2011-11-05)
P E Morgan et al.
Journal of molecular recognition : JMR, 9(5-6), 394-400 (1996-09-01)
The preparation, characterisation and testing of stable non-porous coated perfluorocarbon supports functionalised with the metal chelate, iminodiacetic acid (IDA) is described. Polyvinyl alcohol (PVA), a neutral hydrophilic polymer was esterified with perfluorooctanoyl chloride and anchored to the surface of solid
P B van Wachem et al.
Journal of biomedical materials research, 55(3), 415-423 (2001-03-20)
Calcification limits the long-term durability of xenograft glutaraldehyde (GA)-crosslinked heart valves. Previously, a study in rats showed that epoxy-crosslinked heart valves reduced lymphocyte reactions to the same extent as the GA-crosslinked control and induced a similar foreign-body response and calcification
David Stocks et al.
Journal of drugs in dermatology : JDD, 10(9), 974-980 (2011-11-05)
Hyaluronic acid (HA) gels are commonly injected into the skin to lift rhytides and to improve facial appearance. The different processes used in their manufacture and formulation yield products with unique physical characteristics that play an important role in predicting

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