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T3955

Sigma-Aldrich

TNP

≥95% (HPLC)

Sinónimos:

N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine; N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine; N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine

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About This Item

Fórmula empírica (notación de Hill):
C20H16F3N7O2
Número de CAS:
519178-28-0
Peso molecular:
443.38
Número MDL:
MFCD16875436
Código UNSPSC:
12352200
ID de la sustancia en PubChem:
329826781
NACRES:
NA.77

Nivel de calidad

100

Ensayo

≥95% (HPLC)

Formulario

powder

condiciones de almacenamiento

protect from light

color

yellow

solubilidad

DMSO: ≥10 mg/mL

emisor

Novartis

temp. de almacenamiento

2-8°C

cadena SMILES

[O-][N+](=O)c1ccc(CNc2nc(NCc3cccc(c3)C(F)(F)F)nc4[nH]cnc24)cc1

InChI

1S/C20H16F3N7O2/c21-20(22,23)14-3-1-2-13(8-14)10-25-19-28-17(16-18(29-19)27-11-26-16)24-9-12-4-6-15(7-5-12)30(31)32/h1-8,11H,9-10H2,(H3,24,25,26,27,28,29)

Clave InChI

DDSBPUYZPWNNGH-UHFFFAOYSA-N

Acciones bioquímicas o fisiológicas

Potent and selective IP6K inhibitor; less selective inhibitor of IP3K.
TNP is a potent and selective IP6K inhibitor; less selective inhibitor of IP3K. Discovery of TNP as an inositol trisphosphate (IP3) kinase inhibitor was first reported in 2002, However, a recent reference shows that TNP is more potent as an IP6K inhibitor, making it valuable for study of inositol pyrophosphates.

Características y beneficios

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Nota de preparación

TNP is soluble in DMSO at a concentration that is greater than or equal to 10 mg/ml.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
0000230819
0000219697
0000230818
0000179553
115M4602V

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