SML0956

Dexmedetomidine hydrochloride

≥98% (HPLC)

• Sinónimos: (+)-Medetomidine hydrochloride, (S)-Medetomidine hydrochloride, 4-[(S)-α,2,3-Trimethylbenzyl]imidazole monohydrochloride, 5-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride
• Fórmula empírica (notación de Hill): C₁₃H₁₆N₂ · HCl
• Número de CAS: 145108-58-3
• Peso molecular: 236.74
• UNSPSC Code: 12352200
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D +48 to +58°, c = 1 in H₂O
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: [Cl-].[N+H2]1C=NC=C1[C@@H](C)c2c(c(ccc2)C)C
• InChI: 1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/t11-;/m0./s1
• InChI key: VPNGEIHDPSLNMU-MERQFXBCSA-N

Descripción

Application

Dexmedetomidine hydrochloride has been used to study its effects on primary neonatal rat cardiomyocytes under hypoxic/reoxygenation conditions. It has also been used to study the effects of dexmedetomidine pretreatment on lipopolysaccharide-induced acute lung injury in mice.

Biochem/physiol Actions

Dexmedetomidine hydrochloride is a highly potent and selective α2-adrenergic agonist with analgesic and sedative properties, the (+)-isomer of medetomidine. Dexmedetomidine hydrochloride is used clinically as an anesthetic agent to reduce anxiety and tension and promote relaxation and sedation without causing respiratory depression.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Información de seguridad

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H302,H336,H411
• pcodes: P261 - P264 - P271 - P273 - P301 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable