SML0445

Clemastine fumarate salt

≥98% (HPLC)

• Sinónimos: (+)-2-[2-[(p-Chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methylpyrrolidine fumarate salt, (2R)-2-[2-[(1R)-1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine fumarate salt, 1-Methyl-2-[2-(α-methyl-p-chlorobenzhydryloxy)ethyl]pyrrolidine fumarate salt, 1-Methyl-2-[2-(methyl-p-chlorodiphenylmethyloxy)ethyl]pyrrolidine fumarate salt, Meclastine fumarate salt, Mecloprodine
• Fórmula empírica (notación de Hill): C₂₁H₂₆ClNO · C₄H₄O₄
• Número de CAS: 14976-57-9
• Peso molecular: 459.96
• Número CE: 239-055-2
• Número MDL: MFCD00137486
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 329824727
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥98% (HPLC)
• Formulario: powder
• actividad óptica: [α]/D +15 to +25°, c = 1 in methanol
• condiciones de almacenamiento: desiccated
• color: white to beige
• solubilidad: DMSO: 5 mg/mL (clear solution; warmed)
• temp. de almacenamiento: room temp
• cadena SMILES: OC(=O)\C=C\C(O)=O.CN1CCC[C@@H]1CCO[C@](C)(c2ccccc2)c3ccc(Cl)cc3
• InChI: 1S/C21H26ClNO.C4H4O4/c1-21(17-7-4-3-5-8-17,18-10-12-19(22)13-11-18)24-16-14-20-9-6-15-23(20)2;5-3(6)1-2-4(7)8/h3-5,7-8,10-13,20H,6,9,14-16H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t20-,21-;/m1./s1
• Clave InChI: PMGQWSIVQFOFOQ-YKVZVUFRSA-N
• Información sobre el gen: human ... HRH1(3269)

Descripción

Descripción general

Clemastine fumarate is used to treat multiple sclerosis, sneezing and rhinorrhea linked to common cold. It stimulates oligodendrocyte progenitor cell (OPC) differentiation and myelination.

Aplicación

Clemastine fumarate salt has been used as a stimulator of rodent oligodendrocyte generation and myelination in vitro and in vivo.

Acciones bioquímicas o fisiológicas

Clemastine fumarate is an antihistamine H1-antagonist and anticholinergic that also has antipruritic activity.

Clemastine fumarate is an antihistamine H1-antagonist and anticholinergic.

Características y beneficios

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable