P8396

Piperacillin sodium salt

penicillin analog

• Fórmula empírica (notación de Hill): C₂₃H₂₆N₅NaO₇S
• Número de CAS: 59703-84-3
• Peso molecular: 539.54
• Beilstein: 5373920
• Número CE: 261-868-6
• Número MDL: MFCD00917471
• Código UNSPSC: 51282423
• ID de la sustancia en PubChem: 329820325
• NACRES: NA.85

Propiedades

• Nivel de calidad: 200
• Formulario: powder
• solubilidad: H₂O: soluble 50 mg/mL
• espectro de actividad antibiótica: Gram-negative bacteria; Gram-positive bacteria
• Modo de acción: cell wall synthesis | interferes
• temp. de almacenamiento: 2-8°C
• cadena SMILES: [Na+].CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C([O-])=O)c4ccccc4)C(=O)C1=O
• InChI: 1S/C23H27N5O7S.Na/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28;/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34);/q;+1/p-1/t13-,14-,15+,20-;/m1./s1
• Clave InChI: WCMIIGXFCMNQDS-IDYPWDAWSA-M

Descripción

Descripción general

Chemical structure: ß-lactam

Aplicación

Piperacillin is a semisynthetic, broad-spectrum ureidopenicillin antibiotic. It is derived from ampicillin. It has been used in pharmacokinetic studies in order to optimize antimicrobial therapy in patients with sepsis. It is used to study piperacillin hypersensitivity reactions and to study multidrug-resistant organisms.

Acciones bioquímicas o fisiológicas

Piperacillin inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins (PBPs), which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. Piperacillin may interfere with autolysin inhibitors.

Envase

1g,5g,10g

Otras notas

Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)