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G5011

Sigma-Aldrich

Glucan from baker′s yeast (S. cerevisiae)

≥98.00%

Sinónimos:

Glucosan

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About This Item

Número de CAS:
9012-72-0
EC Number:
232-739-1
MDL number:
MFCD00466924
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

bakers yeast (S. cerevisiae)

Quality Level

200

assay

≥98.00%

form

powder

color

white to faint yellow

solubility

water: 9.80-10.20 mg/mL, turbid, colorless to light yellow

storage temp.

2-8°C

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General description

Glucan is a natural polysaccharide. They are carbohydrates forming structural components, which is found in the cell walls of yeast, fungi, seaweed and cereals.

Application

Glucan from baker′s yeast (S. cerevisiae) has been used:
  • for immune stimulation
  • to stimulate mRNA expression of a sigma class glutathione S-transferase (GST) in hemocytes
  • to study its effects in rainbow trout intestinal epithelial cell line (RTgutGC)

Biochem/physiol Actions

Glucan enhances anti-infectious immunity, prevents cancer growth, lowers stress and reduces cholesterol level. It has immunostimulatory property. It maintains blood sugar level and rejuvenates skin.

Preparation Note

Prepared by the method of Bacon, et al.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000369290
0000369290
0000350689
0000320036
0000215502

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Sequence features, expression profiles and biochemical characteristics of a sigma class glutathione S-transferase gene (AiGSTsigma) from bay scallop Argopecten irradians
Wang M, et al.
Invertebrate survival journal , 15(1), 19-30 (2017)
Simone J C F M Moorlag et al.
Cell reports, 31(7), 107634-107634 (2020-05-21)
β-glucan is a potent inducer of epigenetic and functional reprogramming of innate immune cells, a process called "trained immunity," resulting in an enhanced host response against secondary infections. We investigate whether β-glucan exposure confers protection against pulmonary Mycobacterium tuberculosis (Mtb)
Jeyachandran Sivakamavalli et al.
Journal of molecular recognition : JMR, 29(5), 186-198 (2015-12-22)
In invertebrates, the prophenoloxidase (proPO) pathway is involved in the phenol-like antioxidant production against invading pathogens. Overproduction of melanin and phenolic substances leads to the disruption of hemocytes (own host cells); therefore, there is a prerequisite to regulate the antioxidant
Glucan supplementation enhances the immune response against an influenza challenge in mice
Vetvicka V and Vetvickova J
Annals of Translational Medicine, 3(2) (2015)
Antonella Torosantucci et al.
The Journal of experimental medicine, 202(5), 597-606 (2005-09-09)
To generate a vaccine to protect against a variety of human pathogenic fungi, we conjugated laminarin (Lam), a well-characterized but poorly immunogenic beta-glucan preparation from the brown alga Laminaria digitata, with the diphtheria toxoid CRM197, a carrier protein used in
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