F5012
Anti-Ferritin, Human antibody produced in rabbit
whole antiserum, liquid
Sinónimos:
Anti-FHC, Anti-FTH, Anti-FTHL6, Anti-HFE5, Anti-PIG15, Anti-PLIF
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About This Item
Productos recomendados
origen biológico
rabbit
conjugado
unconjugated
forma del anticuerpo
whole antiserum
tipo de anticuerpo
primary antibodies
clon
polyclonal
Formulario
liquid
contiene
15 mM sodium azide
reactividad de especies
human
técnicas
Ouchterlony double diffusion: 1:16
Nº de acceso UniProt
temp. de almacenamiento
−20°C
modificación del objetivo postraduccional
unmodified
Información sobre el gen
human ... FTH1(2495)
Descripción general
Ferritin, an iron-storage protein is usually present in the liver and spleen in mammals. Iron and ferritin are distributed relatively same in the eye. Ferritin is made up of heavy and light chains.
Inmunógeno
Ferritin isolated from normal human spleen
Aplicación
- Anti-Ferritin, Human antibody produced in rabbit has been used in:
- immunohistochemistry
- western blotting
- immunocytochemical techniques
Anti-Ferritin, Human antibody is suitable for use in Ouchterlony double diffusion (1:16 using human spleen ferritin), and immunoelectrophoresis. The antibody may also be used in western blot (1:1000 using frozen liver homogenates) and immunoprecipitation (using 300 μg of cell lysate incubated with 6 mul of anti-ferritin for 1h at 4 ° C).
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
Acciones bioquímicas o fisiológicas
Ferritin is an iron-storage protein that regulates iron-homeostasis in cells. While mitochondrial ferritin is a homopolymer, the cytosolic form consists of heteropolymeric L- and H-chains. Genetic mutations in ferritin L-chains have been associated with neurodegenerative disorders, whereas altered levels of ferritin have been linked to hemophagocytic lymphohistiocytosis and adult-onset Still′s disease . In immunoelectrophoresis, anti-ferritin, human antibody is specific for ferritin when used against human spleen extract and purified ferritin. No reactivity is observed against normal human serum.
Nota de preparación
The antiserum has been treated to remove lipoproteins.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de clase de almacenamiento
12 - Non Combustible Liquids
Clase de riesgo para el agua (WGK)
nwg
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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Certificados de análisis (COA)
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Los clientes también vieron
Pro-inflammatory activation of microglia in the brain of patients with sepsis
Zrzavy T, et al.
Neuropathology and Applied Neurobiology, 45(3), 278-290 (2019)
Zhao Wang et al.
International journal of hematology, 90(4), 501-505 (2009-08-06)
Elevated levels of serum ferritin and a low percentage of glycosylated ferritin have been reported in adult-onset Still's disease (AOSD) as well as in hemophagocytic lymphohistiocytosis (HLH). The objective of the current study was to investigate total ferritin levels and
Moon-Suhn Ryu et al.
The Journal of clinical investigation, 127(5), 1786-1797 (2017-04-05)
Developing erythrocytes take up exceptionally large amounts of iron, which must be transferred to mitochondria for incorporation into heme. This massive iron flux must be precisely controlled to permit the coordinated synthesis of heme and hemoglobin while avoiding the toxic
Iron-Induced Retinal Damage
Handbook of nutrition, diet, and the eye, 619-626 (2014)
Scientific tests
Aldred EM, et al.
Pharmacology, 331-341 (2009)
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
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