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Merck

D4645

Sigma-Aldrich

Sodium 3,5-dichloro-2-hydroxybenzenesulfonate

≥98% purity (TLC), powder

Sinónimos:

3,5-Dichloro-2-hydroxybenzenesulfonic acid, DCHBS, DHBS

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About This Item

Fórmula empírica (notación de Hill):
C6H3Cl2NaO4S
Número de CAS:
Peso molecular:
265.05
Beilstein/REAXYS Number:
3640643
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

Sodium 3,5-dichloro-2-hydroxybenzenesulfonate, used for peroxide measurement

Quality Level

assay

≥98% (TLC)

form

powder

technique(s)

titration: suitable

color

white to off-white

pH

7 (20 °C, 53 g/L)

mp

>300 °C

solubility

H2O: 50 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].Oc1c(Cl)cc(Cl)cc1S([O-])(=O)=O

InChI

1S/C6H4Cl2O4S.Na/c7-3-1-4(8)6(9)5(2-3)13(10,11)12;/h1-2,9H,(H,10,11,12);/q;+1/p-1

InChI key

NMWCVZCSJHJYFW-UHFFFAOYSA-M

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General description

Sodium 3,5-dichloro-2-hydroxybenzenesulfonate is used in conjunction with 4-aminoantipyrine (4-AAP) and hydrogen peroxide (H2O2) for chromogenic quantitation of uric acid in serum and urine samples.

Application

Used in conjunction with 4-aminoantipyrine (4-AAP) and hydrogen peroxide (H2O2) for chromogenic quantitation of peroxidase in coupled enzymatic reactions. Component of Trinder reagent for use with peroxidase to measure generation of hydrogen peroxide in automated systems.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificados de análisis (COA)

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Teresa Ramon-Marquez et al.
Talanta, 187, 83-90 (2018-06-02)
In this study, we have optimised the sterically directed attachment of biomolecules on the surface of coaxial membranes prepared by co-electrospinning which have been proved to be a material with very high performance for the development of biosensors with optical
Use of 3,5-dichloro-2-hydroxybenzenesulfonic acid/4-aminophenazone chromogenic system in direct enzymatic assay of uric acid in serum and urine.
Fossati P, et al.
Clinical Chemistry, 26(2), 227-231 (1980)
J D Artiss et al.
Clinical chemistry, 30(8), 1389-1392 (1984-08-01)
A colorimetric peroxidase-coupled procedure for determination of creatinine in human serum and urine is described. A 30-s sample pre-treatment with bilirubin oxidase eliminates interference from endogenous bilirubin. The 4-aminoantipyrine-2-hydroxy-3,5-dichlorobenzenesulfonate chromogen system of this method is about fourfold more sensitive than
J D Artiss et al.
Clinica chimica acta; international journal of clinical chemistry, 116(3), 301-309 (1981-11-11)
A uricase-peroxidase coupled system, for the determination of uric acid, applied to a CentrifiChem-500 centrifugal fast analyser is described. Relatively large amounts of ascorbic acid, due to the inclusion of an ascorbate oxidase urine diluent, and hemoglobin appear not to
Seulgi Ju et al.
Frontiers in plant science, 8, 1210-1210 (2017-07-27)
The cuticle of land plants is the first physical barrier to protect their aerial parts from biotic and abiotic stresses. DEWAX, an AP2/ERF-type transcription factor, negatively regulates cuticular wax biosynthesis. In this study, we investigated the resistance to

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