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Merck
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200R-1

Sigma-Aldrich

Androgen Receptor (SP107) Rabbit Monoclonal Antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
clone:
SP107, monoclonal
application:
IHC (p)
species reactivity:
human
technique(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
citations:
7

biological source

rabbit

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

SP107, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (200R-14)
vial of 0.5 mL concentrate (200R-15)
bottle of 1.0 mL predilute (200R-17)
vial of 1.0 mL concentrate (200R-16)
bottle of 7.0 mL predilute (200R-18)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

isotype

IgG

control

prostate

shipped in

wet ice

storage temp.

2-8°C

visualization

nuclear

Categorías relacionadas

General description

As a member of the steroid hormone superfamily, androgen receptor functions within distinctintracellular compartments to mediate cellular growth and transcriptional activation ofandrogen-regulated signaling pathways. Androgen receptor expression is broadly distributedacross a variety of normal tissue types. The anti-androgen receptor may be used as an aid toidentify carcinomas of the breast and prostate.

Quality


IVD
IVD
IVD
RUO

Linkage

Androgen Receptor Positive Control Slides, Product No. 200S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
0000407908
0000407908
0000401996
0000376700
0000376692

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Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

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A K Roy et al.
Annals of the New York Academy of Sciences, 949, 44-57 (2002-01-25)
Androgens are C-19 steroids secreted primarily from the testes and adrenals that play a critical role in reproduction. Reproductive functions of androgens are mediated through coordination of diverse physiological processes ranging from brain functions to specific cell proliferation and apoptosis.
Laura C Collins et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 24(7), 924-931 (2011-05-10)
Previous studies have demonstrated that androgen receptor is expressed in many breast cancers, but its expression in relation to the various breast cancer subtypes as defined by molecular profiling has not been studied in detail. We constructed tissue microarrays from
L O Gonzalez et al.
Histopathology, 50(7), 866-874 (2007-06-05)
To evaluate the expression of androgen receptors (AR) and two androgen-induced proteins [apolipoprotein D (ApoD) and pepsinogen C (PepC)] in ductal carcinoma in situ (DCIS) of the breast. AR, ApoD and PepC expression was examined in 28 cases of pure
Claire Bléchet et al.
Virchows Archiv : an international journal of pathology, 450(4), 433-439 (2007-03-03)
Previous studies have shown that C cells are twice as numerous in male than in female thyroids and that C cell hyperplasia (CCH) is much more frequent in men. These findings suggest regulation involving sex steroid hormones through the expression
R S Carroll et al.
Journal of neurosurgery, 82(3), 453-460 (1995-03-01)
The predominance of meningiomas in females, the accelerated growth of these tumors during the luteal phase of the menstrual cycle and during pregnancy, and the association between meningiomas and breast cancer have led to a number of studies examining the
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