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Merck

T32603

Sigma-Aldrich

2-Thiophenecarboxylic acid

ReagentPlus®, 99%

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About This Item

Fórmula empírica (notación de Hill):
C5H4O2S
Número de CAS:
Peso molecular:
128.15
Beilstein/REAXYS Number:
110150
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

product line

ReagentPlus®

assay

99%

bp

260 °C (lit.)

mp

125-127 °C (lit.)

SMILES string

OC(=O)c1cccs1

InChI

1S/C5H4O2S/c6-5(7)4-2-1-3-8-4/h1-3H,(H,6,7)

InChI key

QERYCTSHXKAMIS-UHFFFAOYSA-N

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Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Laval Chan et al.
Bioorganic & medicinal chemistry letters, 14(3), 793-796 (2004-01-27)
The discovery of a novel class of HCV NS5B polymerase inhibitors, 3-arylsulfonylamino-5-phenyl-thiophene-2-carboxylic acids is described. SAR studies have yielded several potent inhibitors of HCV polymerase as well as of HCV subgenomic RNA replication in Huh-7 cells.
Mrinal K Bera et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 17(42), 11838-11843 (2011-09-08)
Herein, we describe our attempts to systematically prepare a series of oligo(2-thienyl)-substituted pyridine derivatives. The crucial starting material, a β-alkoxy-β-ketoenamide, is easily available on a large scale by the reaction of lithiated methoxyallene with thiophene-2-carbonitrile and thiophene-2-carboxylic acid. This three-component
C Savarin et al.
Organic letters, 3(1), 91-93 (2001-06-30)
[figure: see text] A new methodology for the synthesis of substituted alkynes is described. In the presence of copper(I) thiophene-2-carboxylate (CuTC) or copper (I) 3-methylsalicylate (CuMeSal), the palladium-catalyzed cross-coupling of thioalkyne derivatives with boronic acids affords functionalized alkynes in yields
Matthew F McCown et al.
Antimicrobial agents and chemotherapy, 53(5), 2129-2132 (2009-03-11)
In vitro, telaprevir selects subtype-specific resistance pathways for hepatitis C virus GT-1a and GT-1b, as described to have occurred in patients. In GT-1a, the HCV-796 resistance mutation C316Y has low replication capacity (7%) that can be compensated for by the
D Panagoulis et al.
Journal of inorganic biochemistry, 101(4), 623-634 (2007-02-06)
Copper complexes with thiophen-2-yl saturated and alpha,beta-unsaturated carboxylic acids as ligands were prepared, characterized and pharmacochemically studied. The available evidence supports a dimeric structure for the complexes of the general formula [Cu2(L)4(MeOH)2] where L are the anions of thiophene 2-carboxylic

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