64275
Methanesulfonamide
≥97.0% (CHN)
Sinónimos:
Mesylamide, Methanesulfonic amide, Methanesulphonamide
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About This Item
Fórmula lineal:
CH3SO2NH2
Número de CAS:
Peso molecular:
95.12
Beilstein/REAXYS Number:
1740835
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
assay
≥97.0% (CHN)
form
solid
mp
85-89 °C (lit.)
SMILES string
CS(N)(=O)=O
InChI
1S/CH5NO2S/c1-5(2,3)4/h1H3,(H2,2,3,4)
InChI key
HNQIVZYLYMDVSB-UHFFFAOYSA-N
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Categorías relacionadas
Application
- Methanesulfonamide is used in the synthesis of important organic reagents such as N-(2-methylthio-1-p-toluenesufonyl)methanesulfonamide and tert-butyl ((2-(trimethylsilyl)ethyl)sulfonyl)carbamate.
- It can be used as a source of nitrogen in the conversion of carboxylic acids to corresponding nitriles.
- It is widely used as a reagent in the synthesis of medicinally important compounds such as derivatives of indole-N-acetamide, methanesulfonamide pyrimidine-substituted 3,5-dihydroxy-6-heptenoates and repertaxin.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Aliphatic sulfonamides, as CH3SO2NH2, are very weak inhibitors of the carbonic anhydrases (KI congruent to 10(-4) M) and are extremely weak acids (Ka congruent to 10(-10.5) M). We now find CF3SO2NH2 a very potent inhibitor of carbonic anhydrase II (KI
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