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411035

Sigma-Aldrich

6-Hydroxyflavone

98%

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About This Item

Fórmula empírica (notación de Hill):
C15H10O3
Número de CAS:
6665-83-4
Peso molecular:
238.24
EC Number:
229-704-8
MDL number:
MFCD00017329
UNSPSC Code:
12352100
PubChem Substance ID:
24865723
NACRES:
NA.22

Quality Level

100

assay

98%

form

solid

mp

234-236 °C (lit.)

functional group

ketone
phenyl

SMILES string

Oc1ccc2OC(=CC(=O)c2c1)c3ccccc3

InChI

1S/C15H10O3/c16-11-6-7-14-12(8-11)13(17)9-15(18-14)10-4-2-1-3-5-10/h1-9,16H

InChI key

GPZYYYGYCRFPBU-UHFFFAOYSA-N

Gene Information

rat ... Ar(24208) , Gabra2(29706)

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
0000193887
MKCR4437
MKBX6837V
MKBN3127V
MKBD9548V

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Sigma-Aldrich

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Structure of 6-hydroxyflavone.
Seetharaman J and Rajan SS.
Acta Crystallographica Section C, Structural Chemistry, 48(9), 1714-1715 (1992)
Xing Wang et al.
PloS one, 10(3), e0116409-e0116409 (2015-03-20)
Inflammatory responses by kidney mesangial cells play a critical role in the glomerulonephritis. The anti-inflammatory potential of nineteen mono-, di- and polyhydroxylated flavones including fisetin, quercetin, morin, tricetin, gossypetin, apigenin and myricetin were investigated on rat mesangial cells with lipopolysaccharide
Zia Ud Din et al.
Histology and histopathology, 35(10), 1197-1209 (2020-09-11)
In this study, the flavonoid, 6-hydroxyflavone was investigated for its renal protective activity in the cisplatin rat model of nephrotoxicity. Male Sprague-Dawley rats weighing 200-250 g were included in the study. 6-Hydroxyflavone was daily administered at 25 and 50 mg/kg
Sourav Das et al.
Journal of biomolecular structure & dynamics, 37(15), 4019-4034 (2018-10-14)
The interaction of 6-hydroxyflavone (6HF) with hen egg white lysozyme (HEWL) has been executed using multi-spectroscopic and computational methods. Steady state fluorescence studies indicated that static quenching mechanism is involved in the binding of 6HF with HEWL, which was further
Chien-Hung Lai et al.
Evidence-based complementary and alternative medicine : eCAM, 2014, 924560-924560 (2014-05-06)
Osteoblast differentiation plays an essential role in bone integrity. Isoflavones and some flavonoids are reported to have osteogenic activity and potentially possess the ability to treat osteoporosis. However, limited information concerning the osteogenic characteristics of hydroxyflavones is available. This study
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