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F1010

Sigma-Aldrich

Anti-Mouse Polyvalent Immunoglobulins (G,A,M)−FITC antibody produced in goat

affinity isolated antibody, buffered aqueous solution

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

goat

Quality Level

conjugate

FITC conjugate

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

buffered aqueous solution

technique(s)

direct immunofluorescence: 1:256

storage temp.

2-8°C

target post-translational modification

unmodified

General description

Immunoglobulins are proteins produced by B cells in response to antigen and regulate response to bacteria, and viruses. IgG is the main antibody type found in plasma and extracellular fluid and has a pivotal role in complement fixation and placental transport. IgA has a crucial role in mucosal immunity as it restricts pathogens from entering the mucosal membrane. IgM is the largest antibody having a pentameric structure which regulates polyreactivity and removes apoptotic cells. Anti-mouse polyvalent immunoglobulins (G,A,M)−FITC antibody can be used in direct immunofluorescence and immunoelectrophoresis. Goat anti-mouse polyvalent immunoglobulins (G,A,M)-FITC antibody reacts specifically with mouse IgG, IgA, or IgM.

Immunogen

Purified mouse IgG, IgA and IgM

Application

Anti-mouse polyvalent immunoglobulins (G,A,M)−FITC antibody can be used in immunohistochemistry and flow cytometry.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A Gonzalez-Ruiz et al.
Journal of clinical microbiology, 30(11), 2807-2813 (1992-11-01)
Approximately 10% of the world population is infected with Entamoeba histolytica, but only 10% of the carriers develop symptomatic amebiasis. This discrepancy could be explained by the genotypic differences between the morphologically indistinguishable invasive and noninvasive strains of E. histolytica
María Mónica Remedi et al.
International journal of experimental pathology, 90(1), 44-51 (2009-02-10)
The tumour microenvironment, which is largely composed of inflammatory cells, is a crucial participant in the neoplastic process through the promotion of cell proliferation, survival and migration. Neutrophil polymorphonuclear cells (PMNs) induce inflammatory reactions that can be either cytotoxic for
Ricarda Wuestefeld et al.
Glia, 60(6), 936-947 (2012-03-21)
The purpose of the present study was to investigate the effects of vascular endothelial growth factor (VEGF) on gap junctional intercellular communication (GJIC), cell proliferation, and cell dynamics in primary astrocytes. VEGF is known as a dimeric polypeptide that potentially
Xia Yan et al.
Zoological studies, 60, e6-e6 (2021-08-14)
We focused on pathological obesity induced by excessive fat intake (nutritional obesity) in non-hibernator and healthy obesity due to pre-hibernation (PRE) fat storage in hibernator to study the effects of different types of obesity on skeletal muscle protein metabolism and
Marwan Al-Maqtoofi et al.
Environmental microbiology, 18(11), 3620-3634 (2016-02-26)
The fungus Fusarium is well known as a plant pathogen, but has recently emerged as an opportunistic pathogen of humans. Habitats providing direct human exposure to infectious propagules are largely unknown, but there is growing evidence that plumbing systems are

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